Transient receptor potential cation channel subfamily V member 5 (TrpV5) (Calcium transport protein 2) (CaT2) (Epithelial calcium channel 1) (ECaC) (ECaC1) (Osm-9-like TRP channel 3) (OTRPC3)
1_MGGFL 6_ PKAEG 11_ PGSQL 16_ QKLLP 21_ SFLVR 26_ EQDWD 31_ QHLDK 36_ LHMLQ 41_ QKRIL 46_ ESPLL 51_ RASKE 56_ NDLSV 61_ LRQLL 66_ LDCTC 71_ DVRQR 76_ GALGE 81_ TALHI 86_ AALYD 91_ NLEAA 96_ LVLME 101_ AAPEL 106_ VFEPT 111_ TCEAF 116_ AGQTA 121_ LHIAV 126_ VNQNV 131_ NLVRA 136_ LLTRR 141_ ASVSA 146_ RATGT 151_ AFRRS 156_ PRNLI 161_ YFGEH 166_ PLSFA 171_ ACVNS 176_ EEIVR 181_ LLIEH 186_ GADIR 191_ AQDSL 196_ GNTVL 201_ HILIL 206_ QPNKT 211_ FACQM 216_ YNLLL 221_ SYDGH 226_ GDHLQ 231_ PLDLV 236_ PNHQG 241_ LTPFK 246_ LAGVE 251_ GNTVM 256_ FQHLM 261_ QKRRH 266_ IQWTY 271_ GPLTS 276_ ILYDL 281_ TEIDS 286_ WGEEL 291_ SFLEL 296_ VVSSD 301_ KREAR 306_ QILEQ 311_ TPVKE 316_ LVSFK 321_ WNKYG 326_ RPYFC 331_ ILAAL 336_ YLLYM 341_ ICFTT 346_ CCVYR 351_ PLKFR 356_ GGNRT 361_ HSRDI 366_ TILQQ 371_ KLLQE 376_ AYETR 381_ EDIIR 386_ LVGEL 391_ VSIVG 396_ AVIIL 401_ LLEIP 406_ DIFRV 411_ GASRY 416_ FGKTI 421_ LGGPF 426_ HVIII 431_ TYASL 436_ VLVTM 441_ VMRLT 446_ NTNGE 451_ VVPMS 456_ FALVL 461_ GWCSV 466_ MYFTR 471_ GFQML 476_ GPFTI 481_ MIQKM 486_ IFGDL 491_ MRFCW 496_ LMAVV 501_ ILGFA 506_ SAFYI 511_ IFQTE 516_ DPTSL 521_ GQFYD 526_ YPMAL 531_ FTTFE 536_ LFLTV 541_ IDAPA 546_ NYDVD 551_ LPFMF 556_ SIVNF 561_ AFAII 566_ ATLLM 571_ LNLFI 576_ AMMGD 581_ THWRV 586_ AQERD 591_ ELWRA 596_ QVVAT 601_ TVMLE 606_ RKLPR 611_ CLWPR 616_ SGICG 621_ CEFGL 626_ GDRWF 631_ LRVEN 636_ HNDQN 641_ PLRVL 646_ RYVEV 651_ FKNSD 656_ KEDDQ 661_ EHPSE 666_ KQPSG 671_ AESGT 676_ LARAS 681_ LALPT 686_ SSLSR 691_ TASQS 696_ SSHRG 701_ WEILR 706_ QNTLG 711_ HLNLG 716_ LNLSE 721_GDGEE
1: Constitutively active calcium selective cation channel thought to be involved in Ca(2+) reabsorption in kidney and intestine (PubMed:11549322, PubMed:18768590). Required for normal Ca(2+) reabsorption in the kidney distal convoluted tubules (By similarity). The channel is activated by low internal calcium level and the current exhibits an inward rectification (PubMed:11549322, PubMed:18768590). A Ca(2+)-dependent feedback regulation includes fast channel inactivation and slow current decay (By similarity). Heteromeric assembly with TRPV6 seems to modify channel properties. TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating (By similarity)