Histone-lysine N-methyltransferase PRDM7 (EC 2.1.1.-) (PR domain zinc finger protein 7) (PR domain-containing protein 7) ([histone H3]-lysine4 N-methyltransferase PRDM7)
1_MSPER 6_ SQEES 11_ PEGDT 16_ ERTER 21_ KPMVK 26_ DAFKD 31_ ISIYF 36_ TKEEW 41_ AEMGD 46_ WEKTR 51_ YRNVK 56_ MNYNA 61_ LITVG 66_ LRATR 71_ PAFMC 76_ HRRQA 81_ IKLQV 86_ DDTED 91_ SDEEW 96_ TPRQQ 101_ VKPPW 106_ MAFRG 111_ EQSKH 116_ QKGMP 121_ KASFN 126_ NESSL 131_ RELSG 136_ TPNLL 141_ NTSDS 146_ EQAQK 151_ PVSPP 156_ GEAST 161_ SGQHS 166_ RLKLE 171_ LRRKE 176_ TEGKM 181_ YSLRE 186_ RKGHA 191_ YKEIS 196_ EPQDD 201_ DYLYC 206_ EMCQN 211_ FFIDS 216_ CAAHG 221_ PPTFV 226_ KDSAV 231_ DKGHP 236_ NRSAL 241_ SLPPG 246_ LRIGP 251_ SGIPQ 256_ AGLGV 261_ WNEAS 266_ DLPLG 271_ LHFGP 276_ YEGRI 281_ TEDEE 286_ AANSG 291_ YSWLI 296_ TKGRN 301_ CYEYV 306_ DGKDK 311_ SSANW 316_ MRYVN 321_ CARDD 326_ EEQNL 331_ VAFQY 336_ HRQIF 341_ YRTCR 346_ VIRPG 351_ CELLV 356_ WSGDE 361_ YGQEL 366_ GIRSS 371_ IEPAE 376_ SLGQA 381_ VNCWS 386_ GMGMS 391_ MARNW 396_ ASSGA 401_ ASGRK 406_ SSWQG 411_ ENQSQ 416_ RSIHV 421_ PHAVW 426_ PFQVK 431_ NFSVN 436_ MWNAI 441_ TPLRT 446_ SQDHL 451_ QENFS 456_ NQRIP 461_ AQGIR 466_ IRSGN 471_ ILIHA 476_ AVMTK 481_ PKVKR 486_SKKGP
1: Histone methyltransferase that selectively methylates 'Lys-4' of dimethylated histone H3 (H3K4me2) to produce trimethylated 'Lys-4' histone H3 (H3K4me3). May play a role in epigenetic regulation of gene expression by defining an active chromatin state