Basic leucine zipper transcriptional factor ATF-like 3 (B-ATF-3) (21 kDa small nuclear factor isolated from T-cells) (Jun dimerization protein p21SNFT)
1_MSQGL 6_ PAAGS 11_ VLQRS 16_ VAAPG 21_ NQPQP 26_ QPQQQ 31_ SPEDD 36_ DRKVR 41_ RREKN 46_ RVAAQ 51_ RSRKK 56_ QTQKA 61_ DKLHE 66_ EYESL 71_ EQENT 76_ MLRRE 81_ IGKLT 86_ EELKH 91_ LTEAL 96_ KEHEK 101_ MCPLL 106_ LCPMN 111_ FVPVP 116_ PRPDP 121_VAGCL
1: AP-1 family transcription factor that controls the differentiation of CD8(+) thymic conventional dendritic cells in the immune system. Required for development of CD8-alpha(+) classical dendritic cells (cDCs) and related CD103(+) dendritic cells that cross-present antigens to CD8 T-cells and produce interleukin-12 (IL12) in response to pathogens (By similarity). Acts via the formation of a heterodimer with JUN family proteins that recognizes and binds DNA sequence 5'-TGA[CG]TCA-3' and regulates expression of target genes