Dual oxidase 1 (EC 1.11.1.-) (EC 1.6.3.1) (Large NOX 1) (Long NOX 1) (NADPH thyroid oxidase 1) (Thyroid oxidase 1)
1_MGFCL 6_ ALAWT 11_ LLVGA 16_ WTPLG 21_ AQNPI 26_ SWEVQ 31_ RFDGW 36_ YNNLM 41_ EHRWG 46_ SKGSR 51_ LQRLV 56_ PASYA 61_ DGVYQ 66_ PLGEP 71_ HLPNP 76_ RDLSN 81_ TISRG 86_ PAGLA 91_ SLRNR 96_ TVLGV 101_ FFGYH 106_ VLSDL 111_ VSVET 116_ PGCPA 121_ EFLNI 126_ RIPPG 131_ DPMFD 136_ PDQRG 141_ DVVLP 146_ FQRSR 151_ WDPET 156_ GRSPS 161_ NPRDP 166_ ANQVT 171_ GWLDG 176_ SAIYG 181_ SSHSW 186_ SDALR 191_ SFSRG 196_ QLASG 201_ PDPAF 206_ PRDSQ 211_ NPLLM 216_ WAAPD 221_ PATGQ 226_ NGPRG 231_ LYAFG 236_ AERGN 241_ REPFL 246_ QALGL 251_ LWFRY 256_ HNLWA 261_ QRLAR 266_ QHPDW 271_ EDEEL 276_ FQHAR 281_ KRVIA 286_ TYQNI 291_ AVYEW 296_ LPSFL 301_ QKTLP 306_ EYTGY 311_ RPFLD 316_ PSISS 321_ EFVAA 326_ SEQFL 331_ STMVP 336_ PGVYM 341_ RNASC 346_ HFQGV 351_ INRNS 356_ SVSRA 361_ LRVCN 366_ SYWSR 371_ EHPSL 376_ QSAED 381_ VDALL 386_ LGMAS 391_ QIAER 396_ EDHVL 401_ VEDVR 406_ DFWPG 411_ PLKFS 416_ RTDHL 421_ ASCLQ 426_ RGRDL 431_ GLPSY 436_ TKARA 441_ ALGLS 446_ PITRW 451_ QDINP 456_ ALSRS 461_ NDTVL 466_ EATAA 471_ LYNQD 476_ LSWLE 481_ LLPGG 486_ LLESH 491_ RDPGP 496_ LFSTI 501_ VLEQF 506_ VRLRD 511_ GDRYW 516_ FENTR 521_ NGLFS 526_ KKEIE 531_ EIRNT 536_ TLQDV 541_ LVAVI 546_ NIDPS 551_ ALQPN 556_ VFVWH 561_ KGDPC 566_ PQPRQ 571_ LSTEG 576_ LPACA 581_ PSVVR 586_ DYFEG 591_ SGFGF 596_ GVTIG 601_ TLCCF 606_ PLVSL 611_ LSAWI 616_ VARLR 621_ MRNFK 626_ RLQGQ 631_ DRQSI 636_ VSEKL 641_ VGGME 646_ ALEWQ 651_ GHKEP 656_ CRPVL 661_ VYLQP 666_ GQIRV 671_ VDGRL 676_ TVLRT 681_ IQLQP 686_ PQKVN 691_ FVLSS 696_ NRGRR 701_ TLLLK 706_ IPKEY 711_ DLVLL 716_ FNLEE 721_ ERQAL 726_ VENLR 731_ GALKE 736_ SGLSI 741_ QEWEL 746_ REQEL 751_ MRAAV 756_ TREQR 761_ RHLLE 766_ TFFRH 771_ LFSQV 776_ LDINQ 781_ ADAGT 786_ LPLDS 791_ SQKVR 796_ EALTC 801_ ELSRA 806_ EFAES 811_ LGLKP 816_ QDMFV 821_ ESMFS 826_ LADKD 831_ GNGYL 836_ SFREF 841_ LDILV 846_ VFMKG 851_ SPEEK 856_ SRLMF 861_ RMYDF 866_ DGNGL 871_ ISKDE 876_ FIRML 881_ RSFIE 886_ ISNNC 891_ LSKAQ 896_ LAEVV 901_ ESMFR 906_ ESGFQ 911_ DKEEL 916_ TWEDF 921_ HFMLR 926_ DHNSE 931_ LRFTQ 936_ LCVKG 941_ VEVPE 946_ VIKDL 951_ CRRAS 956_ YISQD 961_ MICPS 966_ PRVSA 971_ RCSRS 976_ DIETE 981_ LTPQR 986_ LQCPM 991_ DTDPP 996_ QEIRR 1001_ RFGKK 1006_ VTSFQ 1011_ PLLFT 1016_ EAHRE 1021_ KFQRS 1026_ CLHQT 1031_ VQQFK 1036_ RFIEN 1041_ YRRHI 1046_ GCVAV 1051_ FYAIA 1056_ GGLFL 1061_ ERAYY 1066_ YAFAA 1071_ HHTGI 1076_ TDTTR 1081_ VGIIL 1086_ SRGTA 1091_ ASISF 1096_ MFSYI 1101_ LLTMC 1106_ RNLIT 1111_ FLRET 1116_ FLNRY 1121_ VPFDA 1126_ AVDFH 1131_ RLIAS 1136_ TAIVL 1141_ TVLHS 1146_ VGHVV 1151_ NVYLF 1156_ SISPL 1161_ SVLSC 1166_ LFPGL 1171_ FHDDG 1176_ SELPQ 1181_ KYYWW 1186_ FFQTV 1191_ PGLTG 1196_ VVLLL 1201_ ILAIM 1206_ YVFAS 1211_ HHFRR 1216_ RSFRG 1221_ FWLTH 1226_ HLYIL 1231_ LYVLL 1236_ IIHGS 1241_ FALIQ 1246_ LPRFH 1251_ IFFLV 1256_ PAIIY 1261_ GGDKL 1266_ VSLSR 1271_ KKVEI 1276_ SVVKA 1281_ ELLPS 1286_ GVTHL 1291_ RFQRP 1296_ QGFEY 1301_ KSGQW 1306_ VRIAC 1311_ LALGT 1316_ TEYHP 1321_ FTLTS 1326_ APHED 1331_ TLSLH 1336_ IRAAG 1341_ PWTTR 1346_ LREIY 1351_ SAPTG 1356_ DRCAR 1361_ YPKLY 1366_ LDGPF 1371_ GEGHQ 1376_ EWHKF 1381_ EVSVL 1386_ VGGGI 1391_ GVTPF 1396_ ASILK 1401_ DLVFK 1406_ SSVSC 1411_ QVFCK 1416_ KIYFI 1421_ WVTRT 1426_ QRQFE 1431_ WLADI 1436_ IREVE 1441_ ENDHQ 1446_ DLVSV 1451_ HIYIT 1456_ QLAEK 1461_ FDLRT 1466_ TMLYI 1471_ CERHF 1476_ QKVLN 1481_ RSLFT 1486_ GLRSI 1491_ THFGR 1496_ PPFEP 1501_ FFNSL 1506_ QEVHP 1511_ QVRKI 1516_ GVFSC 1521_ GPPGM 1526_ TKNVE 1531_ KACQL 1536_ INRQD 1541_ RTHFS 1546_HHYEN
1: Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO and lactoperoxidase/LPO. Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense at the surface of mucosa. May have its own peroxidase activity through its N-terminal peroxidase-like domain