CDC42 small effector protein 1 (CDC42-binding protein SCIP1) (Small effector of CDC42 protein 1)
1_MSEFW 6_ HKLGC 11_ CVVEK 16_ PQPKK 21_ KRRRI 26_ DRTMI 31_ GEPMN 36_ FVHLT 41_ HIGSG 46_ EMGAG 51_ DGLAM 56_ TGAVQ 61_ EQMRS 66_ KGNRD 71_RPWSN
1: Probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, inducing actin filament assembly. Alters CDC42-induced cell shape changes. In activated T-cells, may play a role in CDC42-mediated F-actin accumulation at the immunological synapse. May play a role in early contractile events in phagocytosis in macrophages