SOSS complex subunit C (INTS3- and NABP-interacting protein) (Sensor of single-strand DNA complex subunit C) (Sensor of ssDNA subunit C) (SOSS-C) (Single-stranded DNA-binding protein-interacting protein 1) (SSB-interacting protein 1) (hSSBIP1)
1_MAANS 6_ SGQGF 11_ QNKNR 16_ VAILA 21_ ELDKE 26_ KRKLL 31_ MQNQS 36_ STNHP 41_ GASIA 46_ LSRPS 51_ LNKDF 56_ RDHAE 61_ QQHIA 66_ AQQKA 71_ ALQHA 76_ HAHSS 81_ GYFIT 86_ QDSAF 91_ GNLIL 96_PVLPR
1: Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. The SOSS complex associates with single-stranded DNA at DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways