Regulator of G-protein signaling 18 (RGS18)
1_METTL 6_ LFFSQ 11_ INMCE 16_ SKEKT 21_ FFKLI 26_ HGSGK 31_ EETSK 36_ EAKIR 41_ AKEKR 46_ NRLSL 51_ LVQKP 56_ EFHED 61_ TRSSR 66_ SGHLA 71_ KETRV 76_ SPEEA 81_ VKWGE 86_ SFDKL 91_ LSHRD 96_ GLEAF 101_ TRFLK 106_ TEFSE 111_ ENIEF 116_ WIACE 121_ DFKKS 126_ KGPQQ 131_ IHLKA 136_ KAIYE 141_ KFIQT 146_ DAPKE 151_ VNLDF 156_ HTKEV 161_ ITNSI 166_ TQPTL 171_ HSFDA 176_ AQSRV 181_ YQLME 186_ QDSYT 191_ RFLKS 196_ DIYLD 201_ LMEGR 206_ PQRPT 211_ NLRRR 216_ SRSFT 221_ CNEFQ 226_DVQSD
1: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i) alpha-1, G(i) alpha-2, G(i) alpha-3 and G(q) alpha