Kv channel-interacting protein 2 (KChIP2) (A-type potassium channel modulatory protein 2) (Cardiac voltage-gated potassium channel modulatory subunit) (Potassium channel-interacting protein 2)
1_MRGQG 6_ RKESL 11_ SDSRD 16_ LDGSY 21_ DQLTG 26_ HPPGP 31_ TKKAL 36_ KQRFL 41_ KLLPC 46_ CGPQA 51_ LPSVS 56_ ETLAA 61_ PASLR 66_ PHRPR 71_ LLDPD 76_ SVDDE 81_ FELST 86_ VCHRP 91_ EGLEQ 96_ LQEQT 101_ KFTRK 106_ ELQVL 111_ YRGFK 116_ NECPS 121_ GIVNE 126_ ENFKQ 131_ IYSQF 136_ FPQGD 141_ SSTYA 146_ TFLFN 151_ AFDTN 156_ HDGSV 161_ SFEDF 166_ VAGLS 171_ VILRG 176_ TVDDR 181_ LNWAF 186_ NLYDL 191_ NKDGC 196_ ITKEE 201_ MLDIM 206_ KSIYD 211_ MMGKY 216_ TYPAL 221_ REEAP 226_ REHVE 231_ SFFQK 236_ MDRNK 241_ DGVVT 246_ IEEFI 251_ ESCQK 256_ DENIM 261_RSMQL
1: Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels (PubMed:10676964, PubMed:11287421, PubMed:11684073, PubMed:12297301, PubMed:14623880, PubMed:34997220). Modulates channel density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner (PubMed:10676964, PubMed:11287421, PubMed:11684073, PubMed:12297301, PubMed:14623880, PubMed:34997220). Involved in KCND2 and KCND3 trafficking to the cell surface (PubMed:12829703). May be required for the expression of I(To) currents in the heart (By similarity)