Gene name: GPR173

Uniprot entry:

Q9NS66

Protein names:

Probable G-protein coupled receptor 173 (Super conserved receptor expressed in brain 3)

Protein sequence:

1_MANTT 6_ GEPEE 11_ VSGAL 16_ SPPSA 21_ SAYVK 26_ LVLLG 31_ LIMCV 36_ SLAGN 41_ AILSL 46_ LVLKE 51_ RALHK 56_ APYYF 61_ LLDLC 66_ LADGI 71_ RSAVC 76_ FPFVL 81_ ASVRH 86_ GSSWT 91_ FSALS 96_ CKIVA 101_ FMAVL 106_ FCFHA 111_ AFMLF 116_ CISVT 121_ RYMAI 126_ AHHRF 131_ YAKRM 136_ TLWTC 141_ AAVIC 146_ MAWTL 151_ SVAMA 156_ FPPVF 161_ DVGTY 166_ KFIRE 171_ EDQCI 176_ FEHRY 181_ FKAND 186_ TLGFM 191_ LMLAV 196_ LMAAT 201_ HAVYG 206_ KLLLF 211_ EYRHR 216_ KMKPV 221_ QMVPA 226_ ISQNW 231_ TFHGP 236_ GATGQ 241_ AAANW 246_ IAGFG 251_ RGPMP 256_ PTLLG 261_ IRQNG 266_ HAASR 271_ RLLGM 276_ DEVKG 281_ EKQLG 286_ RMFYA 291_ ITLLF 296_ LLLWS 301_ PYIVA 306_ CYWRV 311_ FVKAC 316_ AVPHR 321_ YLATA 326_ VWMSF 331_ AQAAV 336_ NPIVC 341_ FLLNK 346_ DLKKC 351_ LRTHA 356_ PCWGT 361_ GGAPA 366_PREPY

Protein annotations

Protein functions:

1: Is a receptor for the SMIM20 derived peptides Phoenixin-14 and Phoenixin-20 (By similarity). It mediates the Phoenixin-14 and Phoenixin-20 augmentation of gonadotropin-releasing hormone (GNRH) signaling in the hypothalamus and pituitary gland (By similarity). In the ovary, it mediates the effects of Phoenixin-14 and Phoenixin-20 induced granulosa cell proliferation during follicular growth (PubMed:30933929)