Carbohydrate sulfotransferase 7 (EC 2.8.2.-) (EC 2.8.2.17) (Chondroitin 6-sulfotransferase 2) (C6ST-2) (Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 5) (GST-5) (N-acetylglucosamine 6-O-sulfotransferase 4) (GlcNAc6ST-4) (Gn6st-4)
1_MKGRR 6_ RRRRE 11_ YCKFA 16_ LLLVL 21_ YTLVL 26_ LLVPS 31_ VLDGG 36_ RDGDK 41_ GAEHC 46_ PGLQR 51_ SLGVW 56_ SLEAA 61_ AAGER 66_ EQGAE 71_ ARAAE 76_ EGGAN 81_ QSPRF 86_ PSNLS 91_ GAVGE 96_ AVSRE 101_ KQHIY 106_ VHATW 111_ RTGSS 116_ FLGEL 121_ FNQHP 126_ DVFYL 131_ YEPMW 136_ HLWQA 141_ LYPGD 146_ AESLQ 151_ GALRD 156_ MLRSL 161_ FRCDF 166_ SVLRL 171_ YAPPG 176_ DPAAR 181_ APDTA 186_ NLTTA 191_ ALFRW 196_ RTNKV 201_ ICSPP 206_ LCPGA 211_ PRARA 216_ EVGLV 221_ EDTAC 226_ ERSCP 231_ PVAIR 236_ ALEAE 241_ CRKYP 246_ VVVIK 251_ DVRLL 256_ DLGVL 261_ VPLLR 266_ DPGLN 271_ LKVVQ 276_ LFRDP 281_ RAVHN 286_ SRLKS 291_ RQGLL 296_ RESIQ 301_ VLRTR 306_ QRGDR 311_ FHRVL 316_ LAHGV 321_ GARPG 326_ GQSRA 331_ LPAAP 336_ RADFF 341_ LTGAL 346_ EVICE 351_ AWLRD 356_ LLFAR 361_ GAPAW 366_ LRRRY 371_ LRLRY 376_ EDLVR 381_ QPRAQ 386_ LRRLL 391_ RFSGL 396_ RALAA 401_ LDAFA 406_ LNMTR 411_ GAAYG 416_ ADRPF 421_ HLSAR 426_ DAREA 431_ VHAWR 436_ ERLSR 441_ EQVRQ 446_ VEAAC 451_ APAMR 456_ LLAYP 461_ RSGEE 466_ GDAEQ 471_ PREGE 476_ TPLEM 481_DADGA
1: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues. Preferentially acts on mannose-linked GlcNAc. Also able to catalyze the transfer of sulfate to position 6 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Also acts on core 2 mucin-type oligosaccharide and N-acetyllactosamine oligomer with a lower efficiency. Has weak or no activity toward keratan sulfate and oligosaccharides containing the Galbeta1-4GlcNAc. Catalyzes 6-O-sulfation of beta-benzyl GlcNAc but not alpha- or beta-benzyl GalNAc