GPI mannosyltransferase 2 (EC 2.4.1.-) (GPI mannosyltransferase II) (GPI-MT-II) (Phosphatidylinositol-glycan biosynthesis class V protein) (PIG-V)
1_MWPQD 6_ PSRKE 11_ VLRFA 16_ VSCRI 21_ LTLML 26_ QALFN 31_ AIIPD 36_ HHAEA 41_ FSPPR 46_ LAPSG 51_ FVDQL 56_ VEGLL 61_ GGLSH 66_ WDAEH 71_ FLFIA 76_ EHGYL 81_ YEHNF 86_ AFFPG 91_ FPLAL 96_ LVGTE 101_ LLRPL 106_ RGLLS 111_ LRSCL 116_ LISVA 121_ SLNFL 126_ FFMLA 131_ AVALH 136_ DLGCL 141_ VLHCP 146_ HQSFY 151_ AALLF 156_ CLSPA 161_ NVFLA 166_ AGYSE 171_ ALFAL 176_ LTFSA 181_ MGQLE 186_ RGRVW 191_ TSVLL 196_ FAFAT 201_ GVRSN 206_ GLVSV 211_ GFLMH 216_ SQCQG 221_ FFSSL 226_ TMLNP 231_ LRQLF 236_ KLMAS 241_ LFLSV 246_ FTLGL 251_ PFALF 256_ QYYAY 261_ TQFCL 266_ PGSAR 271_ PIPEP 276_ LVQLA 281_ VDKGY 286_ RIAEG 291_ NEPPW 296_ CFWDV 301_ PLIYS 306_ YIQDV 311_ YWNVG 316_ FLKYY 321_ ELKQV 326_ PNFLL 331_ AAPVA 336_ ILVAW 341_ ATWTY 346_ VTTHP 351_ WLCLT 356_ LGLQR 361_ SKNNK 366_ TLEKP 371_ DLGFL 376_ SPQVF 381_ VYVVH 386_ AAVLL 391_ LFGGL 396_ CMHVQ 401_ VLTRF 406_ LGSST 411_ PIMYW 416_ FPAHL 421_ LQDQE 426_ PLLRS 431_ LKTVP 436_ WKPLA 441_ EDSPP 446_ GQKVP 451_ RNPIM 456_ GLLYH 461_ WKTCS 466_ PVTRY 471_ ILGYF 476_ LTYWL 481_ LGLLL 486_HCNFL
1: Alpha-1,6-mannosyltransferase that catalyzes the transfer of the second mannose, via an alpha-1,6 bond, from a dolichol-phosphate-mannose (Dol-P-Man) to the alpha-D-Man-(1->4)-alpha-D-GlcN-(1->6)-(1-radyl,2-acyl-sn-glycero-3-phospho)-2-acyl-inositol (also termed H2) intermediate to generate an alpha-D-Man-(1->6)-alpha-D-Man-(1->4)-alpha-D-GlcN-(1->6)-(1-radyl,2-acyl-sn-glycero-3-phospho)-2-acyl-inositol (also termed H3) and participates in the seventh step of the glycosylphosphatidylinositol-anchor biosynthesis (PubMed:15623507, PubMed:15720390). Also transfers the second mannose on a 2-PEtn-alpha-D-Man-(1->4)-alpha-D-GlcN-(1->6)-(1-radyl,2-acyl-sn-glycero-3-phospho)-2-acyl-inositol (also termed H5) (By similarity)