Probable ATP-dependent RNA helicase DDX28 (EC 3.6.4.13) (Mitochondrial DEAD box protein 28)
1_MALTR 6_ PVRLF 11_ SLVTR 16_ LLLAP 21_ RRGLT 26_ VRSPD 31_ EPLPV 36_ VRIPV 41_ ALQRQ 46_ LEQRQ 51_ SRRRN 56_ LPRPV 61_ LVRPG 66_ PLLVS 71_ ARRPE 76_ LNQPA 81_ RLTLG 86_ RWERA 91_ PLASQ 96_ GWKSR 101_ RARRD 106_ HFSIE 111_ RAQQE 116_ APAVR 121_ KLSSK 126_ GSFAD 131_ LGLEP 136_ RVLHA 141_ LQEAA 146_ PEVVQ 151_ PTTVQ 156_ SSTIP 161_ SLLRG 166_ RHVVC 171_ AAETG 176_ SGKTL 181_ SYLLP 186_ LLQRL 191_ LGQPS 196_ LDSLP 201_ IPAPR 206_ GLVLV 211_ PSREL 216_ AQQVR 221_ AVAQP 226_ LGRSL 231_ GLLVR 236_ DLEGG 241_ HGMRR 246_ IRLQL 251_ SRQPS 256_ ADVLV 261_ ATPGA 266_ LWKAL 271_ KSRLI 276_ SLEQL 281_ SFLVL 286_ DEADT 291_ LLDES 296_ FLELV 301_ DYILE 306_ KSHIA 311_ EGPAD 316_ LEDPF 321_ NPKAQ 326_ LVLVG 331_ ATFPE 336_ GVGQL 341_ LNKVA 346_ SPDAV 351_ TTITS 356_ SKLHC 361_ IMPHV 366_ KQTFL 371_ RLKGA 376_ DKVAE 381_ LVHIL 386_ KHRDR 391_ AERTG 396_ PSGTV 401_ LVFCN 406_ SSSTV 411_ NWLGY 416_ ILDDH 421_ KIQHL 426_ RLQGQ 431_ MPALM 436_ RVGIF 441_ QSFQK 446_ SSRDI 451_ LLCTD 456_ IASRG 461_ LDSTG 466_ VELVV 471_ NYDFP 476_ PTLQD 481_ YIHRA 486_ GRVGR 491_ VGSEV 496_ PGTVI 501_ SFVTH 506_ PWDVS 511_ LVQKI 516_ ELAAR 521_ RRRSL 526_ PGLAS 531_SVKEP
1: Plays an essential role in facilitating the proper assembly of the mitochondrial large ribosomal subunit and its helicase activity is essential for this function (PubMed:25683708, PubMed:25683715). May be involved in RNA processing or transport. Has RNA and Mg(2+)-dependent ATPase activity (PubMed:11350955)