Gene name: AP5S1

Uniprot entry:

Q9NUS5

Protein names:

AP-5 complex subunit sigma-1 (Adaptor-related protein complex 5 sigma subunit) (Sigma5)

Protein sequence:

1_MVHAF 6_ LIHTL 11_ RAPNT 16_ EDTGL 21_ CRVLY 26_ SCVFG 31_ AEKSP 36_ DDPRP 41_ HGAER 46_ DRLLR 51_ KEQIL 56_ AVARQ 61_ VESMC 66_ RLQQQ 71_ ASGRP 76_ PMDLQ 81_ PQSSD 86_ EQVPL 91_ HEAPR 96_ GAFRL 101_ AAENP 106_ FQEPR 111_ TVVWL 116_ GVLSL 121_ GFALV 126_ LDAHE 131_ NLLLA 136_ EGTLR 141_ LLTRL 146_ LLDHL 151_ RLLAP 156_ STSLL 161_ LRADR 166_ IEGIL 171_ TRFLP 176_ HGQLL 181_ FLNDQ 186_ FVQGL 191_EKEFS

Protein annotations

Protein functions:

1: As part of AP-5, a probable fifth adaptor protein complex it may be involved in endosomal transport. According to PubMed:20613862, it is required for efficient homologous recombination DNA double-strand break repair