U3 small nucleolar ribonucleoprotein protein IMP3 (U3 snoRNP protein IMP3) (BRMS2)
1_MVRKL 6_ KFHEQ 11_ KLLKQ 16_ VDFLN 21_ WEVTD 26_ HNLHE 31_ LRVLR 36_ RYRLQ 41_ RREDY 46_ TRYNQ 51_ LSRAV 56_ RELAR 61_ RLRDL 66_ PERDQ 71_ FRVRA 76_ SAALL 81_ DKLYA 86_ LGLVP 91_ TRGSL 96_ ELCDF 101_ VTASS 106_ FCRRR 111_ LPTVL 116_ LKLRM 121_ AQHLQ 126_ AAVAF 131_ VEQGH 136_ VRVGP 141_ DVVTD 146_ PAFLV 151_ TRSME 156_ DFVTW 161_ VDSSK 166_ IKRHV 171_ LEYNE 176_ERDDF
1: Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing (PubMed:12655004). Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (PubMed:34516797)