Mediator of RNA polymerase II transcription subunit 17 (Activator-recruited cofactor 77 kDa component) (ARC77) (Cofactor required for Sp1 transcriptional activation subunit 6) (CRSP complex subunit 6) (Mediator complex subunit 17) (Thyroid hormone receptor-associated protein complex 80 kDa component) (Trap80) (Transcriptional coactivator CRSP77) (Vitamin D3 receptor-interacting protein complex 80 kDa component) (DRIP80)
1_MSGVR 6_ AVRIS 11_ IESAC 16_ EKQVH 21_ EVGLD 26_ GTETY 31_ LPPLS 36_ MSQNL 41_ ARLAQ 46_ RIDFS 51_ QGSGS 56_ EEEEA 61_ AGTEG 66_ DAQEW 71_ PGAGS 76_ SADQD 81_ DEEGV 86_ VKFQP 91_ SLWPW 96_ DSVRN 101_ NLRSA 106_ LTEMC 111_ VLYDV 116_ LSIVR 121_ DKKFM 126_ TLDPV 131_ SQDAL 136_ PPKQN 141_ PQTLQ 146_ LISKK 151_ KSLAG 156_ AAQIL 161_ LKGAE 166_ RLTKS 171_ VTENQ 176_ ENKLQ 181_ RDFNS 186_ ELLRL 191_ RQHWK 196_ LRKVG 201_ DKILG 206_ DLSYR 211_ SAGSL 216_ FPHHG 221_ TFEVI 226_ KNTDL 231_ DLDKK 236_ IPEDY 241_ CPLDV 246_ QIPSD 251_ LEGSA 256_ YIKVS 261_ IQKQA 266_ PDIGD 271_ LGTVN 276_ LFKRP 281_ LPKSK 286_ PGSPH 291_ WQTKL 296_ EAAQN 301_ VLLCK 306_ EIFAQ 311_ LSREA 316_ VQIKS 321_ QVPHI 326_ VVKNQ 331_ IISQP 336_ FPSLQ 341_ LSISL 346_ CHSSN 351_ DKKSQ 356_ KFATE 361_ KQCPE 366_ DHLYV 371_ LEHNL 376_ HLLIR 381_ EFHKQ 386_ TLSSI 391_ MMPHP 396_ ASAPF 401_ GHKRM 406_ RLSGP 411_ QAFDK 416_ NEINS 421_ LQSSE 426_ GLLEK 431_ IIKQA 436_ KHIFL 441_ RSRAA 446_ ATIDS 451_ LASRI 456_ EDPQI 461_ QAHWS 466_ NINDV 471_ YESSV 476_ KVLIT 481_ SQGYE 486_ QICKS 491_ IQLQL 496_ NIGVE 501_ QIRVV 506_ HRDGR 511_ VITLS 516_ YQEQE 521_ LQDFL 526_ LSQMS 531_ QHQVH 536_ AVQQL 541_ AKVMG 546_ WQVLS 551_ FSNHV 556_ GLGPI 561_ ESIGN 566_ ASAIT 571_ VASPS 576_ GDYAI 581_ SVRNG 586_ PESGS 591_ KIMVQ 596_ FPRNQ 601_ CKDLP 606_ KSDVL 611_ QDNKW 616_ SHLRG 621_ PFKEV 626_ QWNKM 631_ EGRNF 636_ VYKME 641_ LLMSA 646_LSPCL
1: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors