Mediator of RNA polymerase II transcription subunit 9 (Mediator complex subunit 9)
1_MASAG 6_ VAAGR 11_ QAEDV 16_ LPPTS 21_ DQPLP 26_ DTKPL 31_ PPPQP 36_ PPVPA 41_ PQPQQ 46_ SPAPR 51_ PQSPA 56_ RAREE 61_ ENYSF 66_ LPLVH 71_ NIIKC 76_ MDKDS 81_ PEVHQ 86_ DLNAL 91_ KSKFQ 96_ EMRKL 101_ ISTMP 106_ GIHLS 111_ PEQQQ 116_ QQLQS 121_ LREQV 126_ RTKNE 131_ LLQKY 136_ KSLCM 141_FEIPK
1: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors