Protein BEX4 (BEX1-like protein 1) (Brain-expressed X-linked protein 4) (Nerve growth factor receptor-associated protein 3)
1_MESKE 6_ ELAAN 11_ NLNGE 16_ NAQQE 21_ NEGGE 26_ QAPTQ 31_ NEEES 36_ RHLGG 41_ GEGQK 46_ PGGNI 51_ RRGRV 56_ RRLVP 61_ NFRWA 66_ IPNRH 71_ IEHNE 76_ ARDDV 81_ ERFVG 86_ QMMEI 91_ KRKTR 96_ EQQMR 101_ HYMRF 106_ QTPEP 111_DNHYD
1: May play a role in microtubule deacetylation by negatively regulating the SIRT2 deacetylase activity toward alpha-tubulin and thereby participate in the control of cell cycle progression and genomic stability (PubMed:27512957). In absence of reductive stress, acts as a pseudosubstrate for the CRL2(FEM1B) complex: associates with FEM1B via zinc, thereby preventing association between FEM1B and its substrates (By similarity)