PCNA-interacting partner (PARI) (PARP-1 binding protein) (PARP1-binding protein) (PARPBP)
1_MAVFN 6_ QKSVS 11_ DMIKE 16_ FRKNW 21_ RALCN 26_ SERTT 31_ LCGAD 36_ SMLLA 41_ LQLSM 46_ AENNK 51_ QHSGE 56_ FTVSL 61_ SDVLL 66_ TWKYL 71_ LHEKL 76_ NLPVE 81_ NMDVT 86_ DHYED 91_ VRKIY 96_ DDFLK 101_ NSNML 106_ DLIDV 111_ YQKCR 116_ ALTSN 121_ CENYN 126_ TVSPS 131_ QLLDF 136_ LSGKQ 141_ YAVGD 146_ ETDLS 151_ IPTSP 156_ TSKYN 161_ RDNEK 166_ VQLLA 171_ RKIIF 176_ SYLNL 181_ LVNSK 186_ NDLAV 191_ AYILN 196_ IPDRG 201_ LGREA 206_ FTDLK 211_ HAARE 216_ KQMSI 221_ FLVAT 226_ SFIRT 231_ IELGG 236_ KGYAP 241_ PPSDP 246_ LRTHV 251_ KGLSN 256_ FINFI 261_ DKLDE 266_ ILGEI 271_ PNPSI 276_ AGGQI 281_ LSVIK 286_ MQLIK 291_ GQNSR 296_ DPFCK 301_ AIEEV 306_ AQDLD 311_ LRIKN 316_ IINSQ 321_ EGVVA 326_ LSTTD 331_ ISPAR 336_ PKSHA 341_ INHGT 346_ AYCGR 351_ DTVKA 356_ LLVLL 361_ DEEAA 366_ NAPTK 371_ NKAEL 376_ LYDEE 381_ NTIHH 386_ HGTSI 391_ LTLFR 396_ SPTQV 401_ NNSIK 406_ PLRER 411_ ICVSM 416_ QEKKI 421_ KMKQT 426_ LIRSQ 431_ FACTY 436_ KDDYM 441_ ISKDN 446_ WNNVN 451_ LASKP 456_ LCVLY 461_ MENDL 466_ SEGVN 471_ PSVGR 476_ STIGT 481_ SFGNV 486_ HLDRS 491_ KNEKV 496_ SRKST 501_ SQTGN 506_ KSSKR 511_ KQVDL 516_ DGENI 521_ LCDNR 526_ NEPPQ 531_ HKNAK 536_ IPKKS 541_ NDSQN 546_ RLYGK 551_ LAKVA 556_ KSNKC 561_ TAKDK 566_ LISGQ 571_AKLTQ
1: Required to suppress inappropriate homologous recombination, thereby playing a central role DNA repair and in the maintenance of genomic stability. Antagonizes homologous recombination by interfering with the formation of the RAD51-DNA homologous recombination structure. Binds single-strand DNA and poly(A) homopolymers. Positively regulate the poly(ADP-ribosyl)ation activity of PARP1; however such function may be indirect