Rhomboid-related protein 2 (RRP2) (EC 3.4.21.105) (Rhomboid-like protein 2) [Cleaved into: Rhomboid-related protein 2, N-terminal fragment (NTF); Rhomboid-related protein 2, C-terminal fragment (CTF)]
1_MAAVH 6_ DLEME 11_ SMNLN 16_ MGREM 21_ KEELE 26_ EEEKM 31_ REDGG 36_ GKDRA 41_ KSKKV 46_ HRIVS 51_ KWMLP 56_ EKSRG 61_ TYLER 66_ ANCFP 71_ PPVFI 76_ ISISL 81_ AELAV 86_ FIYYA 91_ VWKPQ 96_ KQWIT 101_ LDTGI 106_ LESPF 111_ IYSPE 116_ KREEA 121_ WRFIS 126_ YMLVH 131_ AGVQH 136_ ILGNL 141_ CMQLV 146_ LGIPL 151_ EMVHK 156_ GLRVG 161_ LVYLA 166_ GVIAG 171_ SLASS 176_ IFDPL 181_ RYLVG 186_ ASGGV 191_ YALMG 196_ GYFMN 201_ VLVNF 206_ QEMIP 211_ AFGIF 216_ RLLII 221_ ILIIV 226_ LDMGF 231_ ALYRR 236_ FFVPE 241_ DGSPV 246_ SFAAH 251_ IAGGF 256_ AGMSI 261_ GYTVF 266_ SCFDK 271_ ALLKD 276_ PRFWI 281_ AIAAY 286_ LACVL 291_ FAVFF 296_NIFLS
1: Involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors. Known substrate: EFNB3