Mediator of RNA polymerase II transcription subunit 29 (Intersex-like protein) (Mediator complex subunit 29)
1_MAASQ 6_ QQASA 11_ ASSAA 16_ GVSGP 21_ SSAGG 26_ PGPQQ 31_ QPQPP 36_ AQLVG 41_ PAQSG 46_ LLQQQ 51_ QQDFD 56_ PVQRY 61_ KMLIP 66_ QLKES 71_ LQTLM 76_ KVAAQ 81_ NLIQN 86_ TNIDN 91_ GQKSS 96_ DGPIQ 101_ RFDKC 106_ LEEFY 111_ ALCDQ 116_ LELCL 121_ RLAHE 126_ CLSQS 131_ CDSAK 136_ HSPTL 141_ VPTAT 146_ KPDAV 151_ QPDSL 156_ PYPQY 161_ LAVIK 166_ AQISC 171_ AKDIH 176_ TALLD 181_ CANKV 186_ TGKTP 191_APPAG
1: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors