U3 small nucleolar RNA-associated protein 6 homolog (Hepatocellular carcinoma-associated antigen 66) (Multiple hat domains protein)
1_MAEII 6_ QERIE 11_ DRLPE 16_ LEQLE 21_ RIGLF 26_ SHAEI 31_ KAIIK 36_ KASDL 41_ EYKIQ 46_ RRTLF 51_ KEDFI 56_ NYVQY 61_ EINLL 66_ ELIQR 71_ RRTRI 76_ GYSFK 81_ KDEIE 86_ NSIVH 91_ RVQGV 96_ FQRAS 101_ AKWKD 106_ DVQLW 111_ LSYVA 116_ FCKKW 121_ ATKTR 126_ LSKVF 131_ SAMLA 136_ IHSNK 141_ PALWI 146_ MAAKW 151_ EMEDR 156_ LSSES 161_ ARQLF 166_ LRALR 171_ FHPEC 176_ PKLYK 181_ EYFRM 186_ ELMHA 191_ EKLRK 196_ EKEEF 201_ EKASM 206_ DVENP 211_ DYSEE 216_ ILKGE 221_ LAWII 226_ YKNSV 231_ SIIKG 236_ AEFHV 241_ SLLSI 246_ AQLFD 251_ FAKDL 256_ QKEIY 261_ DDLQA 266_ LHTDD 271_ PLTWD 276_ YVARR 281_ ELEIE 286_ SQTEE 291_ QPTTK 296_ QAKAV 301_ EVGRK 306_ EERCC 311_ AVYEE 316_ AVKTL 321_ PTEAM 326_ WKCYI 331_ TFCLE 336_ RFTKK 341_ SNSGF 346_ LRGKR 351_ LERTM 356_ TVFRK 361_ AHELK 366_ LLSEC 371_ QYKQL 376_ SVSLL 381_ CYNFL 386_ REALE 391_ VAVAG 396_ TELFR 401_ DSGTM 406_ WQLKL 411_ QVLIE 416_ SKSPD 421_ IAMLF 426_ EEAFV 431_ HLKPQ 436_ VCLPL 441_ WISWA 446_ EWSEG 451_ AKSQE 456_ DTEAV 461_ FKKAL 466_ LAVIG 471_ ADSVT 476_ LKNKY 481_ LDWAY 486_ RSGGY 491_ KKARA 496_ VFKSL 501_ QESRP 506_ FSVDF 511_ FRKMI 516_ QFEKE 521_ QESCN 526_ MANIR 531_ EYYER 536_ ALREF 541_ GSADS 546_ DLWMD 551_ YMKEE 556_ LNHPL 561_ GRPEN 566_ CGQIY 571_ WRAMK 576_ MLQGE 581_ SAEAF 586_ VAKHA 591_MHQTG
1: Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. Involved in nucleolar processing of pre-18S ribosomal RNA