SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.4.-) (HepA-related protein) (hHARP) (Sucrose nonfermenting protein 2-like 1)
1_MSLPL 6_ TEEQR 11_ KKIEE 16_ NRQKA 21_ LARRA 26_ EKLLA 31_ EQHQR 36_ TSSGT 41_ SIAGN 46_ PFQAK 51_ QGPSQ 56_ NFPRE 61_ SCKPV 66_ SHGVI 71_ FKQQN 76_ LSSSS 81_ NADQR 86_ PHDSH 91_ SFQAK 96_ GIWKK 101_ PEEMP 106_ TACPG 111_ HSPRS 116_ QMALT 121_ GISPP 126_ LAQSP 131_ PEVPK 136_ QQLLS 141_ YELGQ 146_ GHAQA 151_ SPEIR 156_ FTPFA 161_ NPTHK 166_ PLAKP 171_ KSSQE 176_ TPAHS 181_ SGQPP 186_ RDAKL 191_ EAKTA 196_ KASPS 201_ GQNIS 206_ YIHSS 211_ SESVT 216_ PRTEG 221_ RLQQK 226_ SGSSV 231_ QKGVN 236_ SQKGK 241_ CVRNG 246_ DRFQV 251_ LIGYN 256_ AELIA 261_ VFKTL 266_ PSKNY 271_ DPDTK 276_ TWNFS 281_ MNDYS 286_ ALMKA 291_ AQSLP 296_ TVNLQ 301_ PLEWA 306_ YGSSE 311_ SPSTS 316_ SEGQA 321_ GLPSA 326_ PSLSF 331_ VKGRC 336_ MLISR 341_ AYFEA 346_ DISYS 351_ QDLIA 356_ LFKQM 361_ DSRRY 366_ DVKTR 371_ KWSFL 376_ LEEHS 381_ KLIAK 386_ VRCLP 391_ QVQLD 396_ PLPTT 401_ LTLAF 406_ ASQLK 411_ KTSLS 416_ LTPDV 421_ PEADL 426_ SEVDP 431_ KLVSN 436_ LMPFQ 441_ RAGVN 446_ FAIAK 451_ GGRLL 456_ LADDM 461_ GLGKT 466_ IQAIC 471_ IAAFY 476_ RKEWP 481_ LLVVV 486_ PSSVR 491_ FTWEQ 496_ AFLRW 501_ LPSLS 506_ PDCIN 511_ VVVTG 516_ KDRLT 521_ AGLIN 526_ IVSFD 531_ LLSKL 536_ EKQLK 541_ TPFKV 546_ VIIDE 551_ SHFLK 556_ NSRTA 561_ RCRAA 566_ MPVLK 571_ VAKRV 576_ ILLSG 581_ TPAMS 586_ RPAEL 591_ YTQII 596_ AVKPT 601_ FFPQF 606_ HAFGL 611_ RYCDA 616_ KRMPW 621_ GWDYS 626_ GSSNL 631_ GELKL 636_ LLEEA 641_ VMLRR 646_ LKSDV 651_ LSQLP 656_ AKQRK 661_ IVVIA 666_ PGRIN 671_ ARTRA 676_ ALDAA 681_ AKEMT 686_ TKDKT 691_ KQQQK 696_ DALIL 701_ FFNRT 706_ AEAKI 711_ PSVIE 716_ YILDL 721_ LESGR 726_ EKFLV 731_ FAHHK 736_ VVLDA 741_ ITQEL 746_ ERKHV 751_ QHIRI 756_ DGSTS 761_ SAERE 766_ DLCQQ 771_ FQLSE 776_ RHAVA 781_ VLSIT 786_ AANMG 791_ LTFSS 796_ ADLVV 801_ FAELF 806_ WNPGV 811_ LIQAE 816_ DRVHR 821_ IGQTS 826_ SVGIH 831_ YLVAK 836_ GTADD 841_ YLWPL 846_ IQEKI 851_ KVLAE 856_ AGLSE 861_ TNFSE 866_ MTEST 871_ DYLYK 876_ DPKQQ 881_ KIYDL 886_ FQKSF 891_ EKEGS 896_ DMELL 901_ EAAES 906_ FDPGS 911_ ASGTS 916_ GSSSQ 921_ NMGDT 926_ LDESS 931_ LTASP 936_ QKKRR 941_ FEFFD 946_NWDSF
1: ATP-dependent annealing helicase that binds selectively to fork DNA relative to ssDNA or dsDNA and catalyzes the rewinding of the stably unwound DNA. Rewinds single-stranded DNA bubbles that are stably bound by replication protein A (RPA). Acts throughout the genome to reanneal stably unwound DNA, performing the opposite reaction of many enzymes, such as helicases and polymerases, that unwind DNA. May play an important role in DNA damage response by acting at stalled replication forks