Gene name: SPG21

Uniprot entry:

Q9NZD8

Protein names:

Maspardin (Acid cluster protein 33) (Spastic paraplegia 21 autosomal recessive Mast syndrome protein) (Spastic paraplegia 21 protein)

Protein sequence:

1_MGEIK 6_ VSPDY 11_ NWFRG 16_ TVPLK 21_ KIIVD 26_ DDDSK 31_ IWSLY 36_ DAGPR 41_ SIRCP 46_ LIFLP 51_ PVSGT 56_ ADVFF 61_ RQILA 66_ LTGWG 71_ YRVIA 76_ LQYPV 81_ YWDHL 86_ EFCDG 91_ FRKLL 96_ DHLQL 101_ DKVHL 106_ FGASL 111_ GGFLA 116_ QKFAE 121_ YTHKS 126_ PRVHS 131_ LILCN 136_ SFSDT 141_ SIFNQ 146_ TWTAN 151_ SFWLM 156_ PAFML 161_ KKIVL 166_ GNFSS 171_ GPVDP 176_ MMADA 181_ IDFMV 186_ DRLES 191_ LGQSE 196_ LASRL 201_ TLNCQ 206_ NSYVE 211_ PHKIR 216_ DIPVT 221_ IMDVF 226_ DQSAL 231_ STEAK 236_ EEMYK 241_ LYPNA 246_ RRAHL 251_ KTGGN 256_ FPYLC 261_ RSAEV 266_ NLYVQ 271_ IHLLQ 276_ FHGTK 281_ YAAID 286_ PSMVS 291_ AEELE 296_ VQKGS 301_LGISQ

Protein annotations

Protein functions:

1: May play a role as a negative regulatory factor in CD4-dependent T-cell activation