Kv channel-interacting protein 1 (KChIP1) (A-type potassium channel modulatory protein 1) (Potassium channel-interacting protein 1) (Vesicle APC-binding protein)
1_MGAVM 6_ GTFSS 11_ LQTKQ 16_ RRPSK 21_ DIAWW 26_ YYQYQ 31_ RDKIE 36_ DELEM 41_ TMVCH 46_ RPEGL 51_ EQLEA 56_ QTNFT 61_ KRELQ 66_ VLYRG 71_ FKNEC 76_ PSGVV 81_ NEDTF 86_ KQIYA 91_ QFFPH 96_ GDAST 101_ YAHYL 106_ FNAFD 111_ TTQTG 116_ SVKFE 121_ DFVTA 126_ LSILL 131_ RGTVH 136_ EKLRW 141_ TFNLY 146_ DINKD 151_ GYINK 156_ EEMMD 161_ IVKAI 166_ YDMMG 171_ KYTYP 176_ VLKED 181_ TPRQH 186_ VDVFF 191_ QKMDK 196_ NKDGI 201_ VTLDE 206_ FLESC 211_ QEDDN 216_ IMRSL 221_QLFQN
1: Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels (PubMed:10676964, PubMed:11423117, PubMed:17187064, PubMed:34552243, PubMed:34997220). Regulates channel density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner (PubMed:10676964, PubMed:11423117, PubMed:17187064, PubMed:34552243, PubMed:34997220). In vitro, modulates KCND1/Kv4.1 and KCND2/Kv4.2 currents (PubMed:34552243). Increases the presence of KCND2 at the cell surface (PubMed:12829703)