Upstream-binding protein 1 (Transcription factor LBP-1)
1_MAWVL 6_ KMDEV 11_ IESGL 16_ VHDFD 21_ ASLSG 26_ IGQEL 31_ GAGAY 36_ SMSDV 41_ LALPI 46_ FKQED 51_ SSLPL 56_ DGETE 61_ HPPFQ 66_ YVMCA 71_ ATSPA 76_ VKLHD 81_ ETLTY 86_ LNQGQ 91_ SYEIR 96_ MLDNR 101_ KMGDM 106_ PEING 111_ KLVKS 116_ IIRVV 121_ FHDRR 126_ LQYTE 131_ HQQLE 136_ GWKWN 141_ RPGDR 146_ LLDLD 151_ IPMSV 156_ GIIDT 161_ RTNPS 166_ QLNAV 171_ EFLWD 176_ PAKRT 181_ SAFIQ 186_ VHCIS 191_ TEFTP 196_ RKHGG 201_ EKGVP 206_ FRIQV 211_ DTFKQ 216_ NENGE 221_ YTDHL 226_ HSASC 231_ QIKVF 236_ KPKGA 241_ DRKQK 246_ TDREK 251_ MEKRT 256_ AHEKE 261_ KYQPS 266_ YDTTI 271_ LTEMR 276_ LEPII 281_ EDAVE 286_ HEQKK 291_ SSKRT 296_ LPADY 301_ GDSLA 306_ KRGSC 311_ SPWPD 316_ APTAY 321_ VNNSP 326_ SPAPT 331_ FTSPQ 336_ QSTCS 341_ VPDSN 346_ SSSPN 351_ HQGDG 356_ ASQTS 361_ GEQIQ 366_ PSATI 371_ QETQQ 376_ WLLKN 381_ RFSSY 386_ TRLFS 391_ NFSGA 396_ DLLKL 401_ TKEDL 406_ VQICG 411_ AADGI 416_ RLYNS 421_ LKSRS 426_ VRPRL 431_ TIYVC 436_ REQPS 441_ STVLQ 446_ GQQQA 451_ ASSAS 456_ ENGSG 461_ APYVY 466_ HAIYL 471_ EEMIA 476_ SEVAR 481_ KLALV 486_ FNIPL 491_ HQINQ 496_ VYRQG 501_ PTGIH 506_ ILVSD 511_ QMVQN 516_ FQDES 521_ CFLFS 526_ TVKAE 531_SSDGI
1: Functions as a transcriptional activator in a promoter context-dependent manner. Modulates the placental expression of CYP11A1. Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2 (By similarity). Involved in regulation of the alpha-globin gene in erythroid cells. Binds strongly to sequences around the HIV-1 initiation site and weakly over the TATA-box. Represses HIV-1 transcription by inhibiting the binding of TFIID to the TATA-box