Mitochondrial carrier homolog 1 (Presenilin-associated protein)
1_MGASD 6_ PEVAP 11_ WARGG 16_ AAGMA 21_ GAGAG 26_ AGARG 31_ GAAAG 36_ VEARA 41_ RDPPP 46_ AHRAH 51_ PRHPR 56_ PAAQP 61_ SARRM 66_ DGGSG 71_ GLGSG 76_ DNAPT 81_ TEALF 86_ VALGA 91_ GVTAL 96_ SHPLL 101_ YVKLL 106_ IQVGH 111_ EPMPP 116_ TLGTN 121_ VLGRK 126_ VLYLP 131_ SFFTY 136_ AKYIV 141_ QVDGK 146_ IGLFR 151_ GLSPR 156_ LMSNA 161_ LSTVT 166_ RGSMK 171_ KVFPP 176_ DEIEQ 181_ VSNKD 186_ DMKTS 191_ LKKVV 196_ KETSY 201_ EMMMQ 206_ CVSRM 211_ LAHPL 216_ HVISM 221_ RCMVQ 226_ FVGRE 231_ AKYSG 236_ VLSSI 241_ GKIFK 246_ EEGLL 251_ GFFVG 256_ LIPHL 261_ LGDVV 266_ FLWGC 271_ NLLAH 276_ FINAY 281_ LVDDS 286_ VSDTP 291_ GGLGN 296_ DQNPG 301_ SQFSQ 306_ ALAIR 311_ SYTKF 316_ VMGIA 321_ VSMLT 326_ YPFLL 331_ VGDLM 336_ AVNNC 341_ GLQAG 346_ LPPYS 351_ PVFKS 356_ WIHCW 361_ KYLSV 366_ QGQLF 371_ RGSSL 376_ LFRRV 381_SSGSC
1: Protein insertase that mediates insertion of transmembrane proteins into the mitochondrial outer membrane (PubMed:36264797). Catalyzes insertion of proteins with alpha-helical transmembrane regions, such as signal-anchored, tail-anchored and multi-pass membrane proteins (By similarity). Does not mediate insertion of beta-barrel transmembrane proteins (By similarity). May play a role in apoptosis (PubMed:12377771)