Gene name: EHD2

Uniprot entry:

Q9NZN4

Protein names:

EH domain-containing protein 2 (PAST homolog 2)

Protein sequence:

1_MFSWL 6_ KRGGA 11_ RGQQP 16_ EAIRT 21_ VTSAL 26_ KELYR 31_ TKLLP 36_ LEEHY 41_ RFGAF 46_ HSPAL 51_ EDADF 56_ DGKPM 61_ VLVAG 66_ QYSTG 71_ KTSFI 76_ QYLLE 81_ QEVPG 86_ SRVGP 91_ EPTTD 96_ CFVAV 101_ MHGDT 106_ EGTVP 111_ GNALV 116_ VDPDK 121_ PFRKL 126_ NPFGN 131_ TFLNR 136_ FMCAQ 141_ LPNQV 146_ LESIS 151_ IIDTP 156_ GILSG 161_ AKQRV 166_ SRGYD 171_ FPAVL 176_ RWFAE 181_ RVDLI 186_ ILLFD 191_ AHKLE 196_ ISDEF 201_ SEAIG 206_ ALRGH 211_ EDKIR 216_ VVLNK 221_ ADMVE 226_ TQQLM 231_ RVYGA 236_ LMWAL 241_ GKVVG 246_ TPEVL 251_ RVYIG 256_ SFWSQ 261_ PLLVP 266_ DNRRL 271_ FELEE 276_ QDLFR 281_ DIQGL 286_ PRHAA 291_ LRKLN 296_ DLVKR 301_ ARLVR 306_ VHAYI 311_ ISYLK 316_ KEMPS 321_ VFGKE 326_ NKKKQ 331_ LILKL 336_ PVIFA 341_ KIQLE 346_ HHISP 351_ GDFPD 356_ CQKMQ 361_ ELLMA 366_ HDFTK 371_ FHSLK 376_ PKLLE 381_ ALDEM 386_ LTHDI 391_ AKLMP 396_ LLRQE 401_ ELEST 406_ EVGVQ 411_ GGAFE 416_ GTHMG 421_ PFVER 426_ GPDEA 431_ MEDGE 436_ EGSDD 441_ EAEWV 446_ VTKDK 451_ SKYDE 456_ IFYNL 461_ APADG 466_ KLSGS 471_ KAKTW 476_ MVGTK 481_ LPNSV 486_ LGRIW 491_ KLSDV 496_ DRDGM 501_ LDDEE 506_ FALAS 511_ HLIEA 516_ KLEGH 521_ GLPAN 526_ LPRRL 531_ VPPSK 536_RRHKG

Protein annotations

Protein functions:

1: ATP- and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis (By similarity). Plays a role in membrane trafficking between the plasma membrane and endosomes (PubMed:17233914). Important for the internalization of GLUT4. Required for fusion of myoblasts to skeletal muscle myotubes. Required for normal translocation of FER1L5 to the plasma membrane (By similarity). Regulates the equilibrium between cell surface-associated and cell surface-dissociated caveolae by constraining caveolae at the cell membrane (PubMed:25588833)