Gene name: RNF181

Uniprot entry:

Q9P0P0

Protein names:

E3 ubiquitin-protein ligase RNF181 (EC 2.3.2.27) (RING finger protein 181)

Protein sequence:

1_MASYF 6_ DEHDC 11_ EPSDP 16_ EQETR 21_ TNMLL 26_ ELARS 31_ LFNRM 36_ DFEDL 41_ GLVVD 46_ WDHHL 51_ PPPAA 56_ KTVVE 61_ NLPRT 66_ VIRGS 71_ QAELK 76_ CPVCL 81_ LEFEE 86_ EETAI 91_ EMPCH 96_ HLFHS 101_ SCILP 106_ WLSKT 111_ NSCPL 116_ CRYEL 121_ PTDDD 126_ TYEEH 131_ RRDKA 136_ RKQQQ 141_ QHRLE 146_NLHGA

Protein annotations

Protein functions:

1: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates (PubMed:18331836). Catalyzes monoubiquitination of 26S proteasome subunit PSMC2/RPT1 (PubMed:24811749)