Voltage-dependent T-type calcium channel subunit alpha-1I (Voltage-gated calcium channel subunit alpha Cav3.3) (Ca(v)3.3)
1_MAESA 6_ SPPSS 11_ SAAAP 16_ AAEPG 21_ VTTEQ 26_ PGPRS 31_ PPSSP 36_ PGLEE 41_ PLDGA 46_ DPHVP 51_ HPDLA 56_ PIAFF 61_ CLRQT 66_ TSPRN 71_ WCIKM 76_ VCNPW 81_ FECVS 86_ MLVIL 91_ LNCVT 96_ LGMYQ 101_ PCDDM 106_ DCLSD 111_ RCKIL 116_ QVFDD 121_ FIFIF 126_ FAMEM 131_ VLKMV 136_ ALGIF 141_ GKKCY 146_ LGDTW 151_ NRLDF 156_ FIVMA 161_ GMVEY 166_ SLDLQ 171_ NINLS 176_ AIRTV 181_ RVLRP 186_ LKAIN 191_ RVPSM 196_ RILVN 201_ LLLDT 206_ LPMLG 211_ NVLLL 216_ CFFVF 221_ FIFGI 226_ IGVQL 231_ WAGLL 236_ RNRCF 241_ LEENF 246_ TIQGD 251_ VALPP 256_ YYQPE 261_ EDDEM 266_ PFICS 271_ LSGDN 276_ GIMGC 281_ HEIPP 286_ LKEQG 291_ RECCL 296_ SKDDV 301_ YDFGA 306_ GRQDL 311_ NASGL 316_ CVNWN 321_ RYYNV 326_ CRTGS 331_ ANPHK 336_ GAINF 341_ DNIGY 346_ AWIVI 351_ FQVIT 356_ LEGWV 361_ EIMYY 366_ VMDAH 371_ SFYNF 376_ IYFIL 381_ LIIVG 386_ SFFMI 391_ NLCLV 396_ VIATQ 401_ FSETK 406_ QREHR 411_ LMLEQ 416_ RQRYL 421_ SSSTV 426_ ASYAE 431_ PGDCY 436_ EEIFQ 441_ YVCHI 446_ LRKAK 451_ RRALG 456_ LYQAL 461_ QSRRQ 466_ ALGPE 471_ APAPA 476_ KPGPH 481_ AKEPR 486_ HYHGK 491_ TKGQG 496_ DEGRH 501_ LGSRH 506_ CQTLH 511_ GPASP 516_ GNDHS 521_ GRELC 526_ PQHSP 531_ LDATP 536_ HTLVQ 541_ PIPAT 546_ LASDP 551_ ASCPC 556_ CQHED 561_ GRRPS 566_ GLGST 571_ DSGQE 576_ GSGSG 581_ SSAGG 586_ EDEAD 591_ GDGAR 596_ SSEDG 601_ ASSEL 606_ GKEEE 611_ EEEQA 616_ DGAVW 621_ LCGDV 626_ WRETR 631_ AKLRG 636_ IVDSK 641_ YFNRG 646_ IMMAI 651_ LVNTV 656_ SMGIE 661_ HHEQP 666_ EELTN 671_ ILEIC 676_ NVVFT 681_ SMFAL 686_ EMILK 691_ LAAFG 696_ LFDYL 701_ RNPYN 706_ IFDSI 711_ IVIIS 716_ IWEIV 721_ GQADG 726_ GLSVL 731_ RTFRL 736_ LRVLK 741_ LVRFM 746_ PALRR 751_ QLVVL 756_ MKTMD 761_ NVATF 766_ CMLLM 771_ LFIFI 776_ FSILG 781_ MHIFG 786_ CKFSL 791_ RTDTG 796_ DTVPD 801_ RKNFD 806_ SLLWA 811_ IVTVF 816_ QILTQ 821_ EDWNV 826_ VLYNG 831_ MASTS 836_ PWASL 841_ YFVAL 846_ MTFGN 851_ YVLFN 856_ LLVAI 861_ LVEGF 866_ QAEGD 871_ ANRSY 876_ SDEDQ 881_ SSSNI 886_ EEFDK 891_ LQEGL 896_ DSSGD 901_ PKLCP 906_ IPMTP 911_ NGHLD 916_ PSLPL 921_ GGHLG 926_ PAGAA 931_ GPAPR 936_ LSLQP 941_ DPMLV 946_ ALGSR 951_ KSSVM 956_ SLGRM 961_ SYDQR 966_ SLSSS 971_ RSSYY 976_ GPWGR 981_ SAAWA 986_ SRRSS 991_ WNSLK 996_ HKPPS 1001_ AEHES 1006_ LLSAE 1011_ RGGGA 1016_ RVCEV 1021_ AADEG 1026_ PPRAA 1031_ PLHTP 1036_ HAHHI 1041_ HHGPH 1046_ LAHRH 1051_ RHHRR 1056_ TLSLD 1061_ NRDSV 1066_ DLAEL 1071_ VPAVG 1076_ AHPRA 1081_ AWRAA 1086_ GPAPG 1091_ HEDCN 1096_ GRMPS 1101_ IAKDV 1106_ FTKMG 1111_ DRGDR 1116_ GEDEE 1121_ EIDYT 1126_ LCFRV 1131_ RKMID 1136_ VYKPD 1141_ WCEVR 1146_ EDWSV 1151_ YLFSP 1156_ ENRFR 1161_ VLCQT 1166_ IIAHK 1171_ LFDYV 1176_ VLAFI 1181_ FLNCI 1186_ TIALE 1191_ RPQIE 1196_ AGSTE 1201_ RIFLT 1206_ VSNYI 1211_ FTAIF 1216_ VGEMT 1221_ LKVVS 1226_ LGLYF 1231_ GEQAY 1236_ LRSSW 1241_ NVLDG 1246_ FLVFV 1251_ SIIDI 1256_ VVSLA 1261_ SAGGA 1266_ KILGV 1271_ LRVLR 1276_ LLRTL 1281_ RPLRV 1286_ ISRAP 1291_ GLKLV 1296_ VETLI 1301_ SSLKP 1306_ IGNIV 1311_ LICCA 1316_ FFIIF 1321_ GILGV 1326_ QLFKG 1331_ KFYHC 1336_ LGVDT 1341_ RNITN 1346_ RSDCM 1351_ AANYR 1356_ WVHHK 1361_ YNFDN 1366_ LGQAL 1371_ MSLFV 1376_ LASKD 1381_ GWVNI 1386_ MYNGL 1391_ DAVAV 1396_ DQQPV 1401_ TNHNP 1406_ WMLLY 1411_ FISFL 1416_ LIVSF 1421_ FVLNM 1426_ FVGVV 1431_ VENFH 1436_ KCRQH 1441_ QEAEE 1446_ ARRRE 1451_ EKRLR 1456_ RLEKK 1461_ RRKAQ 1466_ RLPYY 1471_ ATYCH 1476_ TRLLI 1481_ HSMCT 1486_ SHYLD 1491_ IFITF 1496_ IICLN 1501_ VVTMS 1506_ LEHYN 1511_ QPTSL 1516_ ETALK 1521_ YCNYM 1526_ FTTVF 1531_ VLEAV 1536_ LKLVA 1541_ FGLRR 1546_ FFKDR 1551_ WNQLD 1556_ LAIVL 1561_ LSVMG 1566_ ITLEE 1571_ IEINA 1576_ ALPIN 1581_ PTIIR 1586_ IMRVL 1591_ RIARV 1596_ LKLLK 1601_ MATGM 1606_ RALLD 1611_ TVVQA 1616_ LPQVG 1621_ NLGLL 1626_ FMLLF 1631_ FIYAA 1636_ LGVEL 1641_ FGKLV 1646_ CNDEN 1651_ PCEGM 1656_ SRHAT 1661_ FENFG 1666_ MAFLT 1671_ LFQVS 1676_ TGDNW 1681_ NGIMK 1686_ DTLRD 1691_ CTHDE 1696_ RSCLS 1701_ SLQFV 1706_ SPLYF 1711_ VSFVL 1716_ TAQFV 1721_ LINVV 1726_ VAVLM 1731_ KHLDD 1736_ SNKEA 1741_ QEDAE 1746_ MDAEL 1751_ ELEMA 1756_ HGLGP 1761_ GPRLP 1766_ TGSPG 1771_ APGRG 1776_ PGGAG 1781_ GGGDT 1786_ EGGLC 1791_ RRCYS 1796_ PAQEN 1801_ LWLDS 1806_ VSLII 1811_ KDSLE 1816_ GELTI 1821_ IDNLS 1826_ GSIFH 1831_ HYSSP 1836_ AGCKK 1841_ CHHDK 1846_ QEVQL 1851_ AETEA 1856_ FSLNS 1861_ DRSSS 1866_ ILLGD 1871_ DLSLE 1876_ DPTAC 1881_ PPGRK 1886_ DSKGE 1891_ LDPPE 1896_ PMRVG 1901_ DLGEC 1906_ FFPLS 1911_ STAVS 1916_ PDPEN 1921_ FLCEM 1926_ EEIPF 1931_ NPVRS 1936_ WLKHD 1941_ SSQAP 1946_ PSPFS 1951_ PDASS 1956_ PLLPM 1961_ PAEFF 1966_ HPAVS 1971_ ASQKG 1976_ PEKGT 1981_ GTGTL 1986_ PKIAL 1991_ QGSWA 1996_ SLRSP 2001_ RVNCT 2006_ LLRQA 2011_ TGSDT 2016_ SLDAS 2021_ PSSSA 2026_ GSLQT 2031_ TLEDS 2036_ LTLSD 2041_ SPRRA 2046_ LGPPA 2051_ PAPGP 2056_ RAGLS 2061_ PAARR 2066_ RLSLR 2071_ GRGLF 2076_ SLRGL 2081_ RAHQR 2086_ SHSSG 2091_ GSTSP 2096_ GCTHH 2101_ DSMDP 2106_ SDEEG 2111_ RGGAG 2116_ GGGAG 2121_ SEHSE 2126_ TLSSL 2131_ SLTSL 2136_ FCPPP 2141_ PPPAP 2146_ GLTPA 2151_ RKFSS 2156_ TSSLA 2161_ APGRP 2166_ HAAAL 2171_ AHGLA 2176_ RSPSW 2181_ AADRS 2186_ KDPPG 2191_ RAPLP 2196_ MGLGP 2201_ LAPPP 2206_ QPLPG 2211_ ELEPG 2216_DAASK
1: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the 'low-voltage activated (LVA)' group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite negative potentials, and a voltage-dependent inactivation. T-type channels serve pacemaking functions in both central neurons and cardiac nodal cells and support calcium signaling in secretory cells and vascular smooth muscle. They may also be involved in the modulation of firing patterns of neurons which is important for information processing as well as in cell growth processes. Gates in voltage ranges similar to, but higher than alpha 1G or alpha 1H
2: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents
3: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents