Actin-related protein 3B (ARP3-beta) (Actin-like protein 3B) (Actin-related protein ARP4)
1_MAGSL 6_ PPCVV 11_ DCGTG 16_ YTKLG 21_ YAGNT 26_ EPQFI 31_ IPSCI 36_ AIRES 41_ AKVVD 46_ QAQRR 51_ VLRGV 56_ DDLDF 61_ FIGDE 66_ AIDKP 71_ TYATK 76_ WPIRH 81_ GIIED 86_ WDLME 91_ RFMEQ 96_ VVFKY 101_ LRAEP 106_ EDHYF 111_ LMTEP 116_ PLNTP 121_ ENREY 126_ LAEIM 131_ FESFN 136_ VPGLY 141_ IAVQA 146_ VLALA 151_ ASWTS 156_ RQVGE 161_ RTLTG 166_ IVIDS 171_ GDGVT 176_ HVIPV 181_ AEGYV 186_ IGSCI 191_ KHIPI 196_ AGRDI 201_ TYFIQ 206_ QLLRE 211_ REVGI 216_ PPEQS 221_ LETAK 226_ AIKEK 231_ YCYIC 236_ PDIVK 241_ EFAKY 246_ DVDPR 251_ KWIKQ 256_ YTGIN 261_ AINQK 266_ KFVID 271_ VGYER 276_ FLGPE 281_ IFFHP 286_ EFANP 291_ DFMES 296_ ISDVV 301_ DEVIQ 306_ NCPID 311_ VRRPL 316_ YKNVV 321_ LSGGS 326_ TMFRD 331_ FGRRL 336_ QRDLK 341_ RVVDA 346_ RLRLS 351_ EELSG 356_ GRIKP 361_ KPVEV 366_ QVVTH 371_ HMQRY 376_ AVWFG 381_ GSMLA 386_ STPEF 391_ FQVCH 396_ TKKDY 401_ EEYGP 406_ SICRH 411_NPVFG
1: Plays a role in the organization of the actin cytoskeleton. May function as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. May decrease the metastatic potential of tumors