Cleavage and polyadenylation specificity factor subunit 2 (Cleavage and polyadenylation specificity factor 100 kDa subunit) (CPSF 100 kDa subunit)
1_MTSII 6_ KLTTL 11_ SGVQE 16_ ESALC 21_ YLLQV 26_ DEFRF 31_ LLDCG 36_ WDEHF 41_ SMDII 46_ DSLRK 51_ HVHQI 56_ DAVLL 61_ SHPDP 66_ LHLGA 71_ LPYAV 76_ GKLGL 81_ NCAIY 86_ ATIPV 91_ YKMGQ 96_ MFMYD 101_ LYQSR 106_ HNTED 111_ FTLFT 116_ LDDVD 121_ AAFDK 126_ IQQLK 131_ FSQIV 136_ NLKGK 141_ GHGLS 146_ ITPLP 151_ AGHMI 156_ GGTIW 161_ KIVKD 166_ GEEEI 171_ VYAVD 176_ FNHKR 181_ EIHLN 186_ GCSLE 191_ MLSRP 196_ SLLIT 201_ DSFNA 206_ TYVQP 211_ RRKQR 216_ DEQLL 221_ TNVLE 226_ TLRGD 231_ GNVLI 236_ AVDTA 241_ GRVLE 246_ LAQLL 251_ DQIWR 256_ TKDAG 261_ LGVYS 266_ LALLN 271_ NVSYN 276_ VVEFS 281_ KSQVE 286_ WMSDK 291_ LMRCF 296_ EDKRN 301_ NPFQF 306_ RHLSL 311_ CHGLS 316_ DLARV 321_ PSPKV 326_ VLASQ 331_ PDLEC 336_ GFSRD 341_ LFIQW 346_ CQDPK 351_ NSIIL 356_ TYRTT 361_ PGTLA 366_ RFLID 371_ NPSEK 376_ ITEIE 381_ LRKRV 386_ KLEGK 391_ ELEEY 396_ LEKEK 401_ LKKEA 406_ AKKLE 411_ QSKEA 416_ DIDSS 421_ DESDI 426_ EEDID 431_ QPSAH 436_ KTKHD 441_ LMMKG 446_ EGSRK 451_ GSFFK 456_ QAKKS 461_ YPMFP 466_ APEER 471_ IKWDE 476_ YGEII 481_ KPEDF 486_ LVPEL 491_ QATEE 496_ EKSKL 501_ ESGLT 506_ NGDEP 511_ MDQDL 516_ SDVPT 521_ KCIST 526_ TESIE 531_ IKARV 536_ TYIDY 541_ EGRSD 546_ GDSIK 551_ KIINQ 556_ MKPRQ 561_ LIIVH 566_ GPPEA 571_ SQDLA 576_ ECCRA 581_ FGGKD 586_ IKVYM 591_ PKLHE 596_ TVDAT 601_ SETHI 606_ YQVRL 611_ KDSLV 616_ SSLQF 621_ CKAKD 626_ AELAW 631_ IDGVL 636_ DMRVS 641_ KVDTG 646_ VILEE 651_ GELKD 656_ DGEDS 661_ EMQVE 666_ APSDS 671_ SVIAQ 676_ QKAMK 681_ SLFGD 686_ DEKET 691_ GEESE 696_ IIPTL 701_ EPLPP 706_ HEVPG 711_ HQSVF 716_ MNEPR 721_ LSDFK 726_ QVLLR 731_ EGIQA 736_ EFVGG 741_ VLVCN 746_ NQVAV 751_ RRTET 756_ GRIGL 761_ EGCLC 766_ QDFYR 771_ IRDLL 776_YEQYA
1: Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. Involved in the histone 3' end pre-mRNA processing