Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial (EC 6.2.1.5) (ATP-specific succinyl-CoA synthetase subunit beta) (A-SCS) (Succinyl-CoA synthetase beta-A chain) (SCS-betaA)
1_MAASM 6_ FYGRL 11_ VAVAT 16_ LRNHR 21_ PRTAQ 26_ RAAAQ 31_ VLGSS 36_ GLFNN 41_ HGLQV 46_ QQQQQ 51_ RNLSL 56_ HEYMS 61_ MELLQ 66_ EAGVS 71_ VPKGY 76_ VAKSP 81_ DEAYA 86_ IAKKL 91_ GSKDV 96_ VIKAQ 101_ VLAGG 106_ RGKGT 111_ FESGL 116_ KGGVK 121_ IVFSP 126_ EEAKA 131_ VSSQM 136_ IGKKL 141_ FTKQT 146_ GEKGR 151_ ICNQV 156_ LVCER 161_ KYPRR 166_ EYYFA 171_ ITMER 176_ SFQGP 181_ VLIGS 186_ SHGGV 191_ NIEDV 196_ AAESP 201_ EAIIK 206_ EPIDI 211_ EEGIK 216_ KEQAL 221_ QLAQK 226_ MGFPP 231_ NIVES 236_ AAENM 241_ VKLYS 246_ LFLKY 251_ DATMI 256_ EINPM 261_ VEDSD 266_ GAVLC 271_ MDAKI 276_ NFDSN 281_ SAYRQ 286_ KKIFD 291_ LQDWT 296_ QEDER 301_ DKDAA 306_ KANLN 311_ YIGLD 316_ GNIGC 321_ LVNGA 326_ GLAMA 331_ TMDII 336_ KLHGG 341_ TPANF 346_ LDVGG 351_ GATVH 356_ QVTEA 361_ FKLIT 366_ SDKKV 371_ LAILV 376_ NIFGG 381_ IMRCD 386_ VIAQG 391_ IVMAV 396_ KDLEI 401_ KIPVV 406_ VRLQG 411_ TRVDD 416_ AKALI 421_ ADSGL 426_ KILAC 431_ DDLDE 436_ AARMV 441_ VKLSE 446_ IVTLA 451_ KQAHV 456_DVKFQ
1: ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA (PubMed:15877282, PubMed:34492704). The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit (By similarity)