Tuftelin-interacting protein 11 (Septin and tuftelin-interacting protein 1) (STIP-1)
1_MSLSH 6_ LYRDG 11_ EGRID 16_ DDDDE 21_ RENFE 26_ ITDWD 31_ LQNEF 36_ NPNRQ 41_ RHWQT 46_ KEEAT 51_ YGVWA 56_ ERDSD 61_ DERPS 66_ FGGKR 71_ ARDYS 76_ APVNF 81_ ISAGL 86_ KKGAA 91_ EEAEL 96_ EDSDD 101_ EEKPV 106_ KQDDF 111_ PKDFG 116_ PRKLK 121_ TGGNF 126_ KPSQK 131_ GFAGG 136_ TKSFM 141_ DFGSW 146_ ERHTK 151_ GIGQK 156_ LLQKM 161_ GYVPG 166_ RGLGK 171_ NAQGI 176_ INPIE 181_ AKQRK 186_ GKGAV 191_ GAYGS 196_ ERTTQ 201_ SMQDF 206_ PVVDS 211_ EEEAE 216_ EEFQK 221_ ELSQW 226_ RKDPS 231_ GSKKK 236_ PKYSY 241_ KTVEE 246_ LKAKG 251_ RISKK 256_ LTAPQ 261_ KELSQ 266_ VKVID 271_ MTGRE 276_ QKVYY 281_ SYSQI 286_ SHKHN 291_ VPDDG 296_ LPLQS 301_ QQLPQ 306_ SGKEA 311_ KAPGF 316_ ALPEL 321_ EHNLQ 326_ LLIDL 331_ TEQEI 336_ IQNDR 341_ QLQYE 346_ RDMVV 351_ NLFHE 356_ LEKMT 361_ EVLDH 366_ EERVI 371_ SNLSK 376_ VLEMV 381_ EECER 386_ RMQPD 391_ CSNPL 396_ TLDEC 401_ ARIFE 406_ TLQDK 411_ YYEEY 416_ RMSDR 421_ VDLAV 426_ AIVYP 431_ LMKEY 436_ FKEWD 441_ PLKDC 446_ TYGTE 451_ IISKW 456_ KSLLE 461_ NDQLL 466_ SHGGQ 471_ DLSAD 476_ AFHRL 481_ IWEVW 486_ MPFVR 491_ NIVTQ 496_ WQPRN 501_ CDPMV 506_ DFLDS 511_ WVHII 516_ PVWIL 521_ DNILD 526_ QLIFP 531_ KLQKE 536_ VENWN 541_ PLTDT 546_ VPIHS 551_ WIHPW 556_ LPLMQ 561_ ARLEP 566_ LYSPI 571_ RSKLS 576_ SALQK 581_ WHPSD 586_ SSAKL 591_ ILQPW 596_ KDVFT 601_ PGSWE 606_ AFMVK 611_ NIVPK 616_ LGMCL 621_ GELVI 626_ NPHQQ 631_ HMDAF 636_ YWVID 641_ WEGMI 646_ SVSSL 651_ VGLLE 656_ KHFFP 661_ KWLQV 666_ LCSWL 671_ SNSPN 676_ YEEIT 681_ KWYLG 686_ WKSMF 691_ SDQVL 696_ AHPSV 701_ KDKFN 706_ EALDI 711_ MNRAV 716_ SSNVG 721_ AYMQP 726_ GAREN 731_ IAYLT 736_ HTERR 741_ KDFQY 746_ EAMQE 751_ RREAE 756_ NMAQR 761_ GIGVA 766_ ASSVP 771_ MNFKD 776_ LIETK 781_ AEEHN 786_ IVFMP 791_ VIGKR 796_ HEGKQ 801_ LYTFG 806_ RIVIY 811_ IDRGV 816_ VFVQG 821_ EKTWV 826_ PTSLQ 831_SLIDM
1: Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP-containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extracellular matrix