Galanin-like peptide
1_MAPPS 6_ VPLVL 11_ LLVLL 16_ LSLAE 21_ TPASA 26_ PAHRG 31_ RGGWT 36_ LNSAG 41_ YLLGP 46_ VLHLP 51_ QMGDQ 56_ DGKRE 61_ TALEI 66_ LDLWK 71_ AIDGL 76_ PYSHP 81_ PQPSK 86_ RNVME 91_ TFAKP 96_ EIGDL 101_ GMLSM 106_ KIPKE 111_EDVLK
1: Hypothalamic neuropeptide which binds to the G-protein-coupled galanin receptors (GALR1, GALR2 and GALR3). Involved in a large number of putative physiological functions in CNS homeostatic processes, including the regulation of gonadotropin-releasing hormone secretion
2: Exhibits potent and dose-dependent vasoconstrictor and anti-edema activity in the cutaneous microvasculature, a physiologic effects which does not appear to be mediated via GALR1 or GALR2. Exhibits antimicrobial activity against Gram-negative bacterias, inducing bacterial membrane blebbing (PubMed:23537644)