P2X purinoceptor 2 (P2X2) (ATP receptor) (Purinergic receptor)
1_MAAAQ 6_ PKYPA 11_ GATAR 16_ RLARG 21_ CWSAL 26_ WDYET 31_ PKVIV 36_ VRNRR 41_ LGVLY 46_ RAVQL 51_ LILLY 56_ FVWYV 61_ FIVQK 66_ SYQES 71_ ETGPE 76_ SSIIT 81_ KVKGI 86_ TTSEH 91_ KVWDV 96_ EEYVK 101_ PPEGG 106_ SVFSI 111_ ITRVE 116_ ATHSQ 121_ TQGTC 126_ PESIR 131_ VHNAT 136_ CLSDA 141_ DCVAG 146_ ELDML 151_ GNGLR 156_ TGRCV 161_ PYYQG 166_ PSKTC 171_ EVFGW 176_ CPVED 181_ GASVS 186_ QFLGT 191_ MAPNF 196_ TILIK 201_ NSIHY 206_ PKFHF 211_ SKGNI 216_ ADRTD 221_ GYLKR 226_ CTFHE 231_ ASDLY 236_ CPIFK 241_ LGFIV 246_ EKAGE 251_ SFTEL 256_ AHKGG 261_ VIGVI 266_ INWDC 271_ DLDLP 276_ ASECN 281_ PKYSF 286_ RRLDP 291_ KHVPA 296_ SSGYN 301_ FRFAK 306_ YYKIN 311_ GTTTR 316_ TLIKA 321_ YGIRI 326_ DVIVH 331_ GQAGK 336_ FSLIP 341_ TIINL 346_ ATALT 351_ SVGVG 356_ SFLCD 361_ WILLT 366_ FMNKN 371_ KVYSH 376_ KKFDK 381_ VCTPS 386_ HPSGS 391_ WPVTL 396_ ARVLG 401_ QAPPE 406_ PGHRS 411_ EDQHP 416_ SPPSG 421_ QEGQQ 426_ GAECG 431_ PAFPP 436_ LRPCP 441_ ISAPS 446_ EQMVD 451_ TPASE 456_ PAQAS 461_ TPTDP 466_KGLAQ
1: ATP-gated nonselective transmembrane cation channel permeable to potassium, sodium and calcium (PubMed:10570044, PubMed:31636190). Activation by extracellular ATP induces a variety of cellular responses, such as excitatory postsynaptic responses in sensory neurons, neuromuscular junctions (NMJ) formation, hearing, perception of taste and peristalsis (By similarity). In the inner ear, regulates sound transduction and auditory neurotransmission, outer hair cell electromotility, inner ear gap junctions, and K(+) recycling (PubMed:23345450). Mediates synaptic transmission between neurons and from neurons to smooth muscle (By similarity)