Voltage-dependent calcium channel gamma-4 subunit (Neuronal voltage-gated calcium channel gamma-4 subunit) (Transmembrane AMPAR regulatory protein gamma-4) (TARP gamma-4)
1_MVRCD 6_ RGLQM 11_ LLTTA 16_ GAFAA 21_ FSLMA 26_ IAIGT 31_ DYWLY 36_ SSAHI 41_ CNGTN 46_ LTMDD 51_ GPPPR 56_ RARGD 61_ LTHSG 66_ LWRVC 71_ CIEGI 76_ YKGHC 81_ FRINH 86_ FPEDN 91_ DYDHD 96_ SSEYL 101_ LRIVR 106_ ASSVF 111_ PILST 116_ ILLLL 121_ GGLCI 126_ GAGRI 131_ YSRKN 136_ NIVLS 141_ AGILF 146_ VAAGL 151_ SNIIG 156_ IIVYI 161_ SSNTG 166_ DPSDK 171_ RDEDK 176_ KNHYN 181_ YGWSF 186_ YFGAL 191_ SFIVA 196_ ETVGV 201_ LAVNI 206_ YIEKN 211_ KELRF 216_ KTKRE 221_ FLKAS 226_ SSSPY 231_ ARMPS 236_ YRYRR 241_ RRSRS 246_ SSRST 251_ EASPS 256_ RDVSP 261_ MGLKI 266_ TGAIP 271_ MGELS 276_ MYTLS 281_ REPLK 286_ VTTAA 291_ SYSPD 296_ QEASF 301_ LQVHD 306_ FFQQD 311_ LKEGF 316_ HVSML 321_NRRTT
1: Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (PubMed:21127204). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization (PubMed:21172611)