PTB domain-containing engulfment adapter protein 1 (Cell death protein 6 homolog) (PTB domain adapter protein CED-6) (Protein GULP)
1_MNRAF 6_ SRKKD 11_ KTWMH 16_ TPEAL 21_ SKHFI 26_ PYNAK 31_ FLGST 36_ EVEQP 41_ KGTEV 46_ VRDAV 51_ RKLKF 56_ ARHIK 61_ KSEGQ 66_ KIPKV 71_ ELQIS 76_ IYGVK 81_ ILEPK 86_ TKEVQ 91_ HNCQL 96_ HRISF 101_ CADDK 106_ TDKRI 111_ FTFIC 116_ KDSES 121_ NKHLC 126_ YVFDS 131_ EKCAE 136_ EITLT 141_ IGQAF 146_ DLAYR 151_ KFLES 156_ GGKDV 161_ ETRKQ 166_ IAGLQ 171_ KRIQD 176_ LETEN 181_ MELKN 186_ KVQDL 191_ ENQLR 196_ ITQVS 201_ APPAG 206_ SMTPK 211_ SPSTD 216_ IFDMI 221_ PFSPI 226_ SHQSS 231_ MPTRN 236_ GTQPP 241_ PVPSR 246_ STEIK 251_ RDLFG 256_ AEPFD 261_ PFNCG 266_ AADFP 271_ PDIQS 276_ KLDEM 281_ QEGFK 286_ MGLTL 291_ EGTVF 296_CLDPL
1: May function as an adapter protein. Required for efficient phagocytosis of apoptotic cells. Modulates cellular glycosphingolipid and cholesterol transport. May play a role in the internalization and endosomal trafficking of various LRP1 ligands, such as PSAP. Increases cellular levels of GTP-bound ARF6