Ribosomal protein S6 kinase beta-2 (S6K-beta-2) (S6K2) (EC 2.7.11.1) (70 kDa ribosomal protein S6 kinase 2) (P70S6K2) (p70-S6K 2) (S6 kinase-related kinase) (SRK) (Serine/threonine-protein kinase 14B) (p70 ribosomal S6 kinase beta) (S6K-beta) (p70 S6 kinase beta) (p70 S6K-beta) (p70 S6KB) (p70-beta)
1_MAAVF 6_ DLDLE 11_ TEEGS 16_ EGEGE 21_ PELSP 26_ ADACP 31_ LAELR 36_ AAGLE 41_ PVGHY 46_ EEVEL 51_ TETSV 56_ NVGPE 61_ RIGPH 66_ CFELL 71_ RVLGK 76_ GGYGK 81_ VFQVR 86_ KVQGT 91_ NLGKI 96_ YAMKV 101_ LRKAK 106_ IVRNA 111_ KDTAH 116_ TRAER 121_ NILES 126_ VKHPF 131_ IVELA 136_ YAFQT 141_ GGKLY 146_ LILEC 151_ LSGGE 156_ LFTHL 161_ EREGI 166_ FLEDT 171_ ACFYL 176_ AEITL 181_ ALGHL 186_ HSQGI 191_ IYRDL 196_ KPENI 201_ MLSSQ 206_ GHIKL 211_ TDFGL 216_ CKESI 221_ HEGAV 226_ THTFC 231_ GTIEY 236_ MAPEI 241_ LVRSG 246_ HNRAV 251_ DWWSL 256_ GALMY 261_ DMLTG 266_ SPPFT 271_ AENRK 276_ KTMDK 281_ IIRGK 286_ LALPP 291_ YLTPD 296_ ARDLV 301_ KKFLK 306_ RNPSQ 311_ RIGGG 316_ PGDAA 321_ DVQRH 326_ PFFRH 331_ MNWDD 336_ LLAWR 341_ VDPPF 346_ RPCLQ 351_ SEEDV 356_ SQFDT 361_ RFTRQ 366_ TPVDS 371_ PDDTA 376_ LSESA 381_ NQAFL 386_ GFTYV 391_ APSVL 396_ DSIKE 401_ GFSFQ 406_ PKLRS 411_ PRRLN 416_ SSPRA 421_ PVSPL 426_ KFSPF 431_ EGFRP 436_ SPSLP 441_ EPTEL 446_ PLPPL 451_ LPPPP 456_ PSTTA 461_ PLPIR 466_ PPSGT 471_ KKSKR 476_GRGRP
1: Phosphorylates specifically ribosomal protein S6 (PubMed:29750193). Seems to act downstream of mTOR signaling in response to growth factors and nutrients to promote cell proliferation, cell growth and cell cycle progression in an alternative pathway regulated by MEAK7 (PubMed:29750193)