Appetite-regulating hormone (Growth hormone secretagogue) (Growth hormone-releasing peptide) (Motilin-related peptide) (Protein M46) [Cleaved into: Ghrelin-27; Ghrelin-28 (Ghrelin); Obestatin]
1_MPSPG 6_ TVCSL 11_ LLLGM 16_ LWLDL 21_ AMAGS 26_ SFLSP 31_ EHQRV 36_ QQRKE 41_ SKKPP 46_ AKLQP 51_ RALAG 56_ WLRPE 61_ DGGQA 66_ EGAED 71_ ELEVR 76_ FNAPF 81_ DVGIK 86_ LSGVQ 91_ YQQHS 96_ QALGK 101_ FLQDI 106_ LWEEA 111_KEAPA
1: Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR) (PubMed:10604470). Induces the release of growth hormone from the pituitary (PubMed:10604470). Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation
2: Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR) (PubMed:10604470). Induces the release of growth hormone from the pituitary (PubMed:10604470). Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation
3: May be the ligand for GPR39. May have an appetite-reducing effect resulting in decreased food intake. May reduce gastric emptying activity and jejunal motility (By similarity)