Gene name: BIN2

Uniprot entry:

Q9UBW5

Protein names:

Bridging integrator 2 (Breast cancer-associated protein 1)

Protein sequence:

1_MAEGK 6_ AGGAA 11_ GLFAK 16_ QVQKK 21_ FSRAQ 26_ EKVLQ 31_ KLGKA 36_ VETKD 41_ ERFEQ 46_ SASNF 51_ YQQQA 56_ EGHKL 61_ YKDLK 66_ NFLSA 71_ VKVMH 76_ ESSKR 81_ VSETL 86_ QEIYS 91_ SEWDG 96_ HEELK 101_ AIVWN 106_ NDLLW 111_ EDYEE 116_ KLADQ 121_ AVRTM 126_ EIYVA 131_ QFSEI 136_ KERIA 141_ KRGRK 146_ LVDYD 151_ SARHH 156_ LEAVQ 161_ NAKKK 166_ DEAKT 171_ AKAEE 176_ EFNKA 181_ QTVFE 186_ DLNQE 191_ LLEEL 196_ PILYN 201_ SRIGC 206_ YVTIF 211_ QNISN 216_ LRDVF 221_ YREMS 226_ KLNHN 231_ LYEVM 236_ SKLEK 241_ QHSNK 246_ VFVVK 251_ GLSSS 256_ SRRSL 261_ VISPP 266_ VRTAT 271_ VSSPL 276_ TSPTS 281_ PSTLS 286_ LKSES 291_ ESVSA 296_ TEDLA 301_ PDAAQ 306_ GEDNS 311_ EIKEL 316_ LEEEE 321_ IEKEG 326_ SEASS 331_ SEEDE 336_ PLPAC 341_ NGPAQ 346_ AQPSP 351_ TTERA 356_ KSQEE 361_ VLPSS 366_ TTPSP 371_ GGALS 376_ PSGQP 381_ SSSAT 386_ EVVLR 391_ TRTAS 396_ EGSEQ 401_ PKKRA 406_ SIQRT 411_ SAPPS 416_ RPPPP 421_ RATAS 426_ PRPSS 431_ GNIPS 436_ SPTAS 441_ GGGSP 446_ TSPRA 451_ SLGTG 456_ TASPR 461_ TSLEV 466_ SPNPE 471_ PPEKP 476_ VRTPE 481_ AKENE 486_ NIHNQ 491_ NPEEL 496_ CTSPT 501_ LMTSQ 506_ VASEP 511_ GEAKK 516_ MEDKE 521_ KDNKL 526_ ISANS 531_ SEGQD 536_ QLQVS 541_ MVPEN 546_ NNLTA 551_ PEPQE 556_EVSTS

Protein annotations

Protein functions:

1: Promotes cell motility and migration, probably via its interaction with the cell membrane and with podosome proteins that mediate interaction with the cytoskeleton. Modulates membrane curvature and mediates membrane tubulation. Plays a role in podosome formation. Inhibits phagocytosis