NK1 transcription factor-related protein 2 (Homeobox protein SAX-1) (NKX-1.1)
1_MLAWQ 6_ DGGAK 11_ AAPSH 16_ HKISF 21_ SVLDI 26_ LDPQK 31_ FTRAA 36_ LPAVR 41_ PAPRE 46_ ARKSL 51_ AEVEA 56_ GKDAS 61_ SRDPV 66_ RQLET 71_ PDAAG 76_ PGAGQ 81_ ASPLE 86_ GSEAE 91_ EEEDA 96_ EDPRR 101_ PRLRE 106_ RAARL 111_ LPGLA 116_ RSPDA 121_ PAGAL 126_ ASGEP 131_ CEDGG 136_ GGPVR 141_ SPPGS 146_ PGSPR 151_ PRRRR 156_ LEPNC 161_ AKPRR 166_ ARTAF 171_ TYEQL 176_ VALEN 181_ KFRAT 186_ RYLSV 191_ CERLN 196_ LALSL 201_ SLTET 206_ QVKIW 211_ FQNRR 216_ TKWKK 221_ QNPGA 226_ DGAAQ 231_ VGGGA 236_ PQPGA 241_ AGGGG 246_ GGGSG 251_ GSPGP 256_ PGTGA 261_ LHFQT 266_ FPSYS 271_ AANVL 276_ FPSAA 281_ SFPLT 286_ AAAPG 291_ SPFAP 296_ FLGPS 301_YLTPF
1: Transcriptional repressor. May play a role in early development as a Wnt/beta-catenin effector, hence controlling pluripotency and preimplantation development of embryonic stem cells. May promote adipogenesis in mesenchymal stem cells, possibly by inhibiting the expression of the antiadipogenic factor NR2F2. May inhibit osteoblastogenic differentiation