Armadillo repeat-containing X-linked protein 3 (ARM protein lost in epithelial cancers on chromosome X 3) (Protein ALEX3)
1_MGYAR 6_ KVGWV 11_ TAGLV 16_ IGAGA 21_ CYCIY 26_ RLTRG 31_ RKQNK 36_ EKMAE 41_ GGSGD 46_ VDDAG 51_ DCSGA 56_ RYNDW 61_ SDDDD 66_ DSNES 71_ KSIVW 76_ YPPWA 81_ RIGTE 86_ AGTRA 91_ RARAR 96_ ARATR 101_ ARRAV 106_ QKRAS 111_ PNSDD 116_ TVLSP 121_ QELQK 126_ VLCLV 131_ EMSEK 136_ PYILE 141_ AALIA 146_ LGNNA 151_ AYAFN 156_ RDIIR 161_ DLGGL 166_ PIVAK 171_ ILNTR 176_ DPIVK 181_ EKALI 186_ VLNNL 191_ SVNAE 196_ NQRRL 201_ KVYMN 206_ QVCDD 211_ TITSR 216_ LNSSV 221_ QLAGL 226_ RLLTN 231_ MTVTN 236_ EYQHM 241_ LANSI 246_ SDFFR 251_ LFSAG 256_ NEETK 261_ LQVLK 266_ LLLNL 271_ AENPA 276_ MTREL 281_ LRAQV 286_ PSSLG 291_ SLFNK 296_ KENKE 301_ VILKL 306_ LVIFE 311_ NINDN 316_ FKWEE 321_ NEPTQ 326_ NQFGE 331_ GSLFF 336_ FLKEF 341_ QVCAD 346_ KVLGI 351_ ESHHD 356_ FLVKV 361_ KVGKF 366_ MAKLA 371_EHMFP
1: Regulates mitochondrial aggregation and transport in axons in living neurons. May link mitochondria to the TRAK2-kinesin motor complex via its interaction with Miro and TRAK2. Mitochondrial distribution and dynamics is regulated through ARMCX3 protein degradation, which is promoted by PCK and negatively regulated by WNT1. Enhances the SOX10-mediated transactivation of the neuronal acetylcholine receptor subunit alpha-3 and beta-4 subunit gene promoters