Post-GPI attachment to proteins factor 2 (FGF receptor-activating protein 1)
1_MYQVP 6_ LPLDR 11_ DGTLV 16_ RLRFT 21_ MVALV 26_ TVCCP 31_ LVAFL 36_ FCILW 41_ SLLFH 46_ FKETT 51_ ATHCG 56_ VPNYL 61_ PSVSS 66_ AIGGE 71_ VPQRY 76_ VWRFC 81_ IGLHS 86_ APRFL 91_ VAFAY 96_ WNHYL 101_ SCTSP 106_ CSCYR 111_ PLCRL 116_ NFGLN 121_ VVENL 126_ ALLVL 131_ TYVSS 136_ SEDFT 141_ IHENA 146_ FIVFI 151_ ASSLG 156_ HMLLT 161_ CILWR 166_ LTKKH 171_ TVSQE 176_ DRKSY 181_ SWKQR 186_ LFIIN 191_ FISFF 196_ SALAV 201_ YFRHN 206_ MYCEA 211_ GVYTI 216_ FAILE 221_ YTVVL 226_ TNMAF 231_ HMTAW 236_ WDFGN 241_ KELLI 246_TSQPE
1: Involved in the fatty acid remodeling steps of GPI-anchor maturation where the unsaturated acyl chain at sn-2 of inositol phosphate is replaced by a saturated stearoyl chain. May catalyze the second step of the fatty acid remodeling, by reacylating a lyso-GPI intermediate at sn-2 of inositol phosphate by a saturated chain (By similarity). The fatty acid remodeling steps is critical for the integration of GPI-APs into lipid rafts (PubMed:23561846)