DNA polymerase subunit gamma-2, mitochondrial (DNA polymerase gamma accessory 55 kDa subunit) (p55) (Mitochondrial DNA polymerase accessory subunit) (MtPolB) (PolG-beta)
1_MRSRV 6_ AVRAC 11_ HKVCR 16_ CLLSG 21_ FGGRV 26_ DAGQP 31_ ELLTE 36_ RSSPK 41_ GGHVK 46_ SHAEL 51_ EGNGE 56_ HPEAP 61_ GSGEG 66_ SEALL 71_ EICQR 76_ RHFLS 81_ GSKQQ 86_ LSRDS 91_ LLSGC 96_ HPGFG 101_ PLGVE 106_ LRKNL 111_ AAEWW 116_ TSVVV 121_ FREQV 126_ FPVDA 131_ LHHKP 136_ GPLLP 141_ GDSAF 146_ RLVSA 151_ ETLRE 156_ ILQDK 161_ ELSKE 166_ QLVAF 171_ LENVL 176_ KTSGK 181_ LRENL 186_ LHGAL 191_ EHYVN 196_ CLDLV 201_ NKRLP 206_ YGLAQ 211_ IGVCF 216_ HPVFD 221_ TKQIR 226_ NGVKS 231_ IGEKT 236_ EASLV 241_ WFTPP 246_ RTSNQ 251_ WLDFW 256_ LRHRL 261_ QWWRK 266_ FAMSP 271_ SNFSS 276_ SDCQD 281_ EEGRK 286_ GNKLY 291_ YNFPW 296_ GKELI 301_ ETLWN 306_ LGDHE 311_ LLHMY 316_ PGNVS 321_ KLHGR 326_ DGRKN 331_ VVPCV 336_ LSVNG 341_ DLDRG 346_ MLAYL 351_ YDSFQ 356_ LTENS 361_ FTRKK 366_ NLHRK 371_ VLKLH 376_ PCLAP 381_ IKVAL 386_ DVGRG 391_ PTLEL 396_ RQVCQ 401_ GLFNE 406_ LLENG 411_ ISVWP 416_ GYLET 421_ MQSSL 426_ EQLYS 431_ KYDEM 436_ SILFT 441_ VLVTE 446_ TTLEN 451_ GLIHL 456_ RSRDT 461_ TMKEM 466_ MHISK 471_ LKDFL 476_IKYIS
1: Accessory subunit of DNA polymerase gamma solely responsible for replication of mitochondrial DNA (mtDNA). Acts as an allosteric regulator of the holoenzyme activities. Enhances the polymerase activity and the processivity of POLG by increasing its interactions with the DNA template. Suppresses POLG exonucleolytic proofreading especially toward homopolymeric templates bearing mismatched termini. Binds to single-stranded DNA