Nuclear receptor-binding protein
1_MSEGE 6_ SQTVL 11_ SSGSD 16_ PKVES 21_ SSSAP 26_ GLTSV 31_ SPPVT 36_ STTSA 41_ ASPEE 46_ EEESE 51_ DESEI 56_ LEESP 61_ CGRWQ 66_ KRREE 71_ VNQRN 76_ VPGID 81_ SAYLA 86_ MDTEE 91_ GVEVV 96_ WNEVQ 101_ FSERK 106_ NYKLQ 111_ EEKVR 116_ AVFDN 121_ LIQLE 126_ HLNIV 131_ KFHKY 136_ WADIK 141_ ENKAR 146_ VIFIT 151_ EYMSS 156_ GSLKQ 161_ FLKKT 166_ KKNHK 171_ TMNEK 176_ AWKRW 181_ CTQIL 186_ SALSY 191_ LHSCD 196_ PPIIH 201_ GNLTC 206_ DTIFI 211_ QHNGL 216_ IKIGS 221_ VAPDT 226_ INNHV 231_ KTCRE 236_ EQKNL 241_ HFFAP 246_ EYGEV 251_ TNVTT 256_ AVDIY 261_ SFGMC 266_ ALEMA 271_ VLEIQ 276_ GNGES 281_ SYVPQ 286_ EAISS 291_ AIQLL 296_ EDPLQ 301_ REFIQ 306_ KCLQS 311_ EPARR 316_ PTARE 321_ LLFHP 326_ ALFEV 331_ PSLKL 336_ LAAHC 341_ IVGHQ 346_ HMIPE 351_ NALEE 356_ ITKNM 361_ DTSAV 366_ LAEIP 371_ AGPGR 376_ EPVQT 381_ LYSQS 386_ PALEL 391_ DKFLE 396_ DVRNG 401_ IYPLT 406_ AFGLP 411_ RPQQP 416_ QQEEV 421_ TSPVV 426_ PPSVK 431_ TPTPE 436_ PAEVE 441_ TRKVV 446_ LMQCN 451_ IESVE 456_ EGVKH 461_ HLTLL 466_ LKLED 471_ KLNRH 476_ LSCDL 481_ MPNEN 486_ IPELA 491_ AELVQ 496_ LGFIS 501_ EADQS 506_ RLTSL 511_ LEETL 516_ NKFNF 521_ ARNST 526_LNSAA
1: Required for embryonic development (By similarity). Plays a role in intestinal epithelial cell fate and proliferation, thereby involved in the architectural development of the intestine potentially via the regulation of Wnt-responsive genes (By similarity). May play a role in subcellular trafficking between the endoplasmic reticulum and Golgi apparatus through interactions with the Rho-type GTPases (PubMed:11956649). Binding to the NS3 protein of dengue virus type 2 appears to subvert this activity into the alteration of the intracellular membrane structure associated with flaviviral replication (PubMed:15084397)