Glutaminase liver isoform, mitochondrial (GLS) (EC 3.5.1.2) (L-glutaminase) (L-glutamine amidohydrolase)
1_MRSMK 6_ ALQKA 11_ LSRAG 16_ SHCGR 21_ GGWGH 26_ PSRSP 31_ LLGGG 36_ VRHHL 41_ SEAAA 46_ QGRET 51_ PHSHQ 56_ PQHQD 61_ HDSSE 66_ SGMLS 71_ RLGDL 76_ LFYTI 81_ AEGQE 86_ RIPIH 91_ KFTTA 96_ LKATG 101_ LQTSD 106_ PRLRD 111_ CMSEM 116_ HRVVQ 121_ ESSSG 126_ GLLDR 131_ DLFRK 136_ CVSSN 141_ IVLLT 146_ QAFRK 151_ KFVIP 156_ DFEEF 161_ TGHVD 166_ RIFED 171_ VKELT 176_ GGKVA 181_ AYIPQ 186_ LAKSN 191_ PDLWG 196_ VSLCT 201_ VDGQR 206_ HSVGH 211_ TKIPF 216_ CLQSC 221_ VKPLT 226_ YAISI 231_ STLGT 236_ DYVHK 241_ FVGKE 246_ PSGLR 251_ YNKLS 256_ LNEEG 261_ IPHNP 266_ MVNAG 271_ AIVVS 276_ SLIKM 281_ DCNKA 286_ EKFDF 291_ VLQYL 296_ NKMAG 301_ NEYMG 306_ FSNAT 311_ FQSEK 316_ ETGDR 321_ NYAIG 326_ YYLKE 331_ KKCFP 336_ KGVDM 341_ MAALD 346_ LYFQL 351_ CSVEV 356_ TCESG 361_ SVMAA 366_ TLANG 371_ GICPI 376_ TGESV 381_ LSAEA 386_ VRNTL 391_ SLMHS 396_ CGMYD 401_ FSGQF 406_ AFHVG 411_ LPAKS 416_ AVSGA 421_ ILLVV 426_ PNVMG 431_ MMCLS 436_ PPLDK 441_ LGNSH 446_ RGTSF 451_ CQKLV 456_ SLFNF 461_ HNYDN 466_ LRHCA 471_ RKLDP 476_ RREGA 481_ EIRNK 486_ TVVNL 491_ LFAAY 496_ SGDVS 501_ ALRRF 506_ ALSAM 511_ DMEQK 516_ DYDSR 521_ TALHV 526_ AAAEG 531_ HIEVV 536_ KFLIE 541_ ACKVN 546_ PFAKD 551_ RWGNI 556_ PLDDA 561_ VQFNH 566_ LEVVK 571_ LLQDY 576_ QDSYT 581_ LSETQ 586_ AEAAA 591_ EALSK 596_ENLES
1: Plays an important role in the regulation of glutamine catabolism. Promotes mitochondrial respiration and increases ATP generation in cells by catalyzing the synthesis of glutamate and alpha-ketoglutarate. Increases cellular anti-oxidant function via NADH and glutathione production. May play a role in preventing tumor proliferation