Tomoregulin-2 (TR-2) (Hyperplastic polyposis protein 1) (Transmembrane protein with EGF-like and two follistatin-like domains)
1_MVLWE 6_ SPRQC 11_ SSWTL 16_ CEGFC 21_ WLLLL 26_ PVMLL 31_ IVARP 36_ VKLAA 41_ FPTSL 46_ SDCQT 51_ PTGWN 56_ CSGYD 61_ DREND 66_ LFLCD 71_ TNTCK 76_ FDGEC 81_ LRIGD 86_ TVTCV 91_ CQFKC 96_ NNDYV 101_ PVCGS 106_ NGESY 111_ QNECY 116_ LRQAA 121_ CKQQS 126_ EILVV 131_ SEGSC 136_ ATDAG 141_ SGSGD 146_ GVHEG 151_ SGETS 156_ QKETS 161_ TCDIC 166_ QFGAE 171_ CDEDA 176_ EDVWC 181_ VCNID 186_ CSQTN 191_ FNPLC 196_ ASDGK 201_ SYDNA 206_ CQIKE 211_ ASCQK 216_ QEKIE 221_ VMSLG 226_ RCQDN 231_ TTTTT 236_ KSEDG 241_ HYART 246_ DYAEN 251_ ANKLE 256_ ESARE 261_ HHIPC 266_ PEHYN 271_ GFCMH 276_ GKCEH 281_ SINMQ 286_ EPSCR 291_ CDAGY 296_ TGQHC 301_ EKKDY 306_ SVLYV 311_ VPGPV 316_ RFQYV 321_ LIAAV 326_ IGTIQ 331_ IAVIC 336_ VVVLC 341_ ITRKC 346_ PRSNR 351_ IHRQK 356_ QNTGH 361_ YSSDN 366_TTRAS
1: May be a survival factor for hippocampal and mesencephalic neurons. The shedded form up-regulates cancer cell proliferation, probably by promoting ERK1/2 phosphorylation