Kinesin-like protein KIF25 (Kinesin-like protein 3)
1_MTWTS 6_ GQLQR 11_ EKQAR 16_ PGSGA 21_ VLAFP 26_ DDKDL 31_ RVYGP 36_ AESQS 41_ AVFGD 46_ VCPLL 51_ TSLLD 56_ GYNVC 61_ VMAYG 66_ QTGSG 71_ KSYTM 76_ LGRHS 81_ DDGPV 86_ LPLDP 91_ QSDLG 96_ IIPRV 101_ AEELF 106_ RLILE 111_ NTSRS 116_ PKVEV 121_ SIVEV 126_ YNNDI 131_ FDLLA 136_ KDSIA 141_ AVSGV 146_ KREVV 151_ TAKDG 156_ RTEVA 161_ LLASE 166_ AVGSA 171_ SKLME 176_ LVHGG 181_ LQLRA 186_ KHPTL 191_ VHADS 196_ SRSHL 201_ IITVT 206_ LTTAS 211_ CSDST 216_ ADQAC 221_ SATLP 226_ REQTE 231_ AGRAG 236_ RSRRA 241_ SQGAL 246_ APQLV 251_ PGNPA 256_ GHAEQ 261_ VQARL 266_ QLVDS 271_ AGSEC 276_ VGVSG 281_ VTGLA 286_ LREMA 291_ CISRS 296_ LAALA 301_ GVLGA 306_ LLEHR 311_ GHAPY 316_ RNSRL 321_ THLLQ 326_ DCLGG 331_ DAKLL 336_ VILCI 341_ SPSQR 346_ HLAQT 351_ LQGLG 356_ FGIRA 361_ RQVQR 366_ GPARK 371_ KPPSS 376_QTEGK
1: Minus-end microtubule-dependent motor protein (By similarity). Acts as a negative regulator of centrosome separation required to prevent premature centrosome separation during interphase (PubMed:28263957). Required to maintain a centered nucleus to ensure that the spindle is stably oriented at the onset of mitosis (PubMed:28263957). May also act as a negative regulator of amino acid starvation-induced autophagy (PubMed:22354037)