Rab5 GDP/GTP exchange factor (RAP1) (Rabaptin-5-associated exchange factor for Rab5) (Rabex-5)
1_MSLKS 6_ ERRGI 11_ HVDQS 16_ DLLCK 21_ KGCGY 26_ YGNPA 31_ WQGFC 36_ SKCWR 41_ EEYHK 46_ ARQKQ 51_ IQEDW 56_ ELAER 61_ LQREE 66_ EEAFA 71_ SSQSS 76_ QGAQS 81_ LTFSK 86_ FEEKK 91_ TNEKT 96_ RKVTT 101_ VKKFF 106_ SASSR 111_ VGSKK 116_ EIQEA 121_ KAPSP 126_ SINRQ 131_ TSIET 136_ DRVSK 141_ EFIEF 146_ LKTFH 151_ KTGQE 156_ IYKQT 161_ KLFLE 166_ GMHYK 171_ RDLSI 176_ EEQSE 181_ CAQDF 186_ YHNVA 191_ ERMQT 196_ RGKVP 201_ PERVE 206_ KIMDQ 211_ IEKYI 216_ MTRLY 221_ KYVFC 226_ PETTD 231_ DEKKD 236_ LAIQK 241_ RIRAL 246_ RWVTP 251_ QMLCV 256_ PVNED 261_ IPEVS 266_ DMVVK 271_ AITDI 276_ IEMDS 281_ KRVPR 286_ DKLAC 291_ ITKCS 296_ KHIFN 301_ AIKIT 306_ KNEPA 311_ SADDF 316_ LPTLI 321_ YIVLK 326_ GNPPR 331_ LQSNI 336_ QYITR 341_ FCNPS 346_ RLMTG 351_ EDGYY 356_ FTNLC 361_ CAVAF 366_ IEKLD 371_ AQSLN 376_ LSQED 381_ FDRYM 386_ SGQTS 391_ PRKQE 396_ AESWS 401_ PDACL 406_ GVKQM 411_ YKNLD 416_ LLSQL 421_ NERQE 426_ RIMNE 431_ AKKLE 436_ KDLID 441_ WTDGI 446_ AREVQ 451_ DIVEK 456_ YPLEI 461_ KPPNQ 466_ PLAAI 471_ DSENV 476_ ENDKL 481_ PPPLQ 486_PQVYA
1: Rab effector protein acting as linker between gamma-adaptin, RAB4A or RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Stimulates nucleotide exchange on RAB5A. Can act as a ubiquitin ligase (By similarity)