Gene name: TRMT6

Uniprot entry:

Q9UJA5

Protein names:

tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 (mRNA methyladenosine-N(1)-methyltransferase non-catalytic subunit TRM6) (tRNA(m1A58)-methyltransferase subunit TRM6) (tRNA(m1A58)MTase subunit TRM6)

Protein sequence:

1_MEGSG 6_ EQPGP 11_ QPQHP 16_ GDHRI 21_ RDGDF 26_ VVLKR 31_ EDVFK 36_ AVQVQ 41_ RRKKV 46_ TFEKQ 51_ WFYLD 56_ NVIGH 61_ SYGTA 66_ FEVTS 71_ GGSLQ 76_ PKKKR 81_ EEPTA 86_ ETKEA 91_ GTDNR 96_ NIVDD 101_ GKSQK 106_ LTQDD 111_ IKALK 116_ DKGIK 121_ GEEIV 126_ QQLIE 131_ NSTTF 136_ RDKTE 141_ FAQDK 146_ YIKKK 151_ KKKYE 156_ AIITV 161_ VKPST 166_ RILSI 171_ MYYAR 176_ EPGKI 181_ NHMRY 186_ DTLAQ 191_ MLTLG 196_ NIRAG 201_ NKMIV 206_ METCA 211_ GLVLG 216_ AMMER 221_ MGGFG 226_ SIIQL 231_ YPGGG 236_ PVRAA 241_ TACFG 246_ FPKSF 251_ LSGLY 256_ EFPLN 261_ KVDSL 266_ LHGTF 271_ SAKML 276_ SSEPK 281_ DSALV 286_ EESNG 291_ TLEEK 296_ QASEQ 301_ ENEDS 306_ MAEAP 311_ ESNHP 316_ EDQET 321_ METIS 326_ QDPEH 331_ KGPKE 336_ RGSKK 341_ DYIQE 346_ KQRRQ 351_ EEQRK 356_ RHLEA 361_ AALLS 366_ ERNAD 371_ GLIVA 376_ SRFHP 381_ TPLLL 386_ SLLDF 391_ VAPSR 396_ PFVVY 401_ CQYKE 406_ PLLEC 411_ YTKLR 416_ ERGGV 421_ INLRL 426_ SETWL 431_ RNYQV 436_ LPDRS 441_ HPKLL 446_ MSGGG 451_ GYLLS 456_ GFTVA 461_ MDNLK 466_ ADTSL 471_ KSNAS 476_ TLESH 481_ ETEEP 486_ AAKKR 491_KCPES

Protein annotations

Protein functions:

1: Substrate-binding subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA (PubMed:16043508). Together with the TRMT61A catalytic subunit, part of a mRNA N(1)-methyltransferase complex that mediates methylation of adenosine residues at the N(1) position of a small subset of mRNAs: N(1) methylation takes place in tRNA T-loop-like structures of mRNAs and is only present at low stoichiometries (PubMed:29072297, PubMed:29107537)